Table 1.

Clinical characteristics of acute respiratory illnesses in patients associated with the four human sequenced coronavirus OC43 (HCoV‐OC43) clinical sample

				Anti‐HCoV‐OC43 serum/ nasal wash reciprocal antibody titers a
Study subject	Age (years)	Gender	Date of illness	Acute illness visit	Convalescent visit	Symptoms/signs of acute respiratory illness	Acute illness severity score b	Acute VAS of severity c	Medical history
2	39	Male	1‐6‐2010	664/<5	1,408/36	Sputum, rhinitis, dyspnea, headache, fatigue, sore throat	45	5	None
3	82	Male	12‐17‐2010	1,983/59	6,758/1,686	Cough, sputum, rhinitis, dyspnea, chills, headache, myalgia, fatigue, sore throat	57	7	COPD d , emphysema, ischemic heart disease, diabetes mellitus
4	61	Male	1‐10‐2011	467/63	7,741/131,410	Cough, sputum, rhinitis, dyspnea, chills, headache, myalgia, body aches and pains, fatigue, sore throat, pharyngitis	80	6	Congestive heart failure, ischemic heart disease, asbestosis, diabetes mellitus
6	62	Male	3‐13‐2012	1,510/139	1,042/460	Rhinitis, dyspnea, chills, body aches and pains, fatigue, sore throat	27	6	Ischemic heart disease, diabetes mellitus, sinusitis

^a Serum antibodies were IgG and nasal wash antibodies were IgA binding to UV light and psoralen‐inactivated tissue culture‐adapted HCoV‐OC43 (ATCC#VR‐1558) measured by enzyme‐linked immunosorbent assay.

^b Severity of influenza‐like symptoms and signs score.

^c VAS is visual analogue scale score.

^d COPD is chronic obstructive pulmonary disease.