Table 4.
Stepwise logistic regression for the effect of prognostic factors on the interferon response in hepatitis C virus (HCV) infected patients
| Regression coefficient | Standard error | Odds ratio | 95% CI for odds ratio | P‐value | ||
|---|---|---|---|---|---|---|
| Lower | Upper | |||||
| Fibrosis (F0–F1 vs F2–F4) | 3.149 | 0.643 | 23.314 | 6.607 | 82.275 | 0.0001 |
| Activity (A0–A1 vs A2–A3 | 1.495 | 0.584 | 4.457 | 1.418 | 14.015 | 0.011 |
| AFP (<5 ng/mL vs >5 ng/mL) | 1.257 | 0.512 | 3.514 | 1.287 | 9.593 | 0.014 |
| OAS Genotype (GG vs GA or AA) | 1.053 | 0.403 | 4.867 | 1.301 | 8.320 | 0.009 |
| OAS Alleles (A vs G) | 1.069 | 0.387 | 4.913 | 1.365 | 8.214 | 0.006 |
P‐values > 0.05 = Not significant; P‐values ≤ 0.05 = Significant.
Multivariate analyses of the different prognostic factors in both sustained virological responder (SVR) and non‐responder (NR) patients including liver fibrosis, liver activity, alpha fetoprotein (AFP), oligoadenylate synthetase (OAS) genotypes and OAS alleles. Data are expressed as number (%).