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This article is being made freely available through PubMed Central as part of the COVID-19 public health emergency response. It can be used for unrestricted research re-use and analysis in any form or by any means with acknowledgement of the original source, for the duration of the public health emergency.
Vaccine Husbandry: Key Points for Veterinary Practitioners
Vaccines have an optimum storage temperature that is usually between 2–8 °C (domestic refrigerators should be maintained at 4 °C). These products should not be frozen or positioned adjacent to the freezer compartment of the refrigerator, and refrigerator temperature should be monitored regularly. Vaccines transported into the field should also be subject to continuation of the ‘cold chain’.
Freeze‐dried vaccines should be reconstituted immediately before use with appropriate diluent or liquid vaccine given simultaneously (as per manufacturer's recommendations). It is bad practice and contraindicated to make up the vaccines anticipated to be used during the day first thing in the morning. Some vaccine components (e.g. CDV, FHV‐1) are particularly labile in this regard and so these vaccines may not induce adequate immunity if not reconstituted just before use.
Vaccines should only be mixed together in the same syringe if this is specified as acceptable in the manufacturer's data sheets.
Syringes and needles for vaccines should not be re‐utilized.
Vaccine injection sites should not be sterilized with alcohol or other disinfectant as this may inactivate infectious (MLV) vaccines.
Vaccines should be ‘in date’ and precise details of batch numbers, components and site of injection should be noted in the animal's medical record.