Table IIIb.
Co‐Occurrence of Respiratory Viruses With Three Main Bacterial Otitis Media Pathogens S. pneumoniae (Pnc), nontypeable H. influenzae (NTHi), and M. catarrhalis (Mc) in the Nasopharynx of Healthy Children With No History of rAOM
| Healthy children, N = 66 | Total, N | With Pnc, N (%) | With NTHi, N (%) | With Mc, N (%) |
|---|---|---|---|---|
| Rhinovirus positive | 28 | 11 (39.3) | 8 (12.1) | 12 (42.9) |
| Rhinovirus negative | 38 | 6 (15.8) | 5 (13.2) | 16 (42.1) |
| P‐value | 0.03 | 0.1 | 1.0 | |
| Bocavirus positive | 13 | 6 (46.2) | 1 (7.7) | 6 (46.2) |
| Bocavirus negative | 53 | 11 (20.8) | 12 (22.6) | 22 (41.5) |
| P‐value | 0.06 | 0.2 | 0.8 | |
| Polyomavirus positive | 10 | 5 (50.0) | 1 (10.0) | 2 (20.0) |
| Polyomavirus negative | 56 | 12 (21.4) | 12 (21.4) | 26 (46.4) |
| P‐value | 0.06 | 0.4 | 0.1 | |
| Parainfluenzavirus positive | 6 | 3 (50.0) | 1 (16.7) | 5 (83.3) |
| Parainfluenzavirus negative | 60 | 14 (23.3) | 12 (20.0) | 23 (38.3) |
| P‐value | 0.2 | 0.9 | 0.03 | |
| Respiratory syncitial virus positive | 6 | 3 (50.0) | 2 (33.3) | 3 (50.0) |
| Respiratory syncitial virus negative | 60 | 14 (23.3) | 11 (18.3) | 25 (41.7) |
| P‐value | 0.2 | 0.4 | 0.7 | |
| Adenovirus positive | 4 | 2 (50.0) | 1 (25.0) | 2 (50.0) |
| Adenovirus negative | 62 | 15 (24.2) | 12 (19.4) | 26 (41.9) |
| P‐value | 0.3 | 0.8 | 0.8 | |
| Coronavirus positive | 4 | 1 (25.0) | 1 (25.0) | 3 (75.0) |
| Coronavirus negative | 62 | 16 (25.8) | 12 (19.4) | 25 (40.3) |
| P‐value | 0.9 | 0.8 | 0.2 | |
| Enterovirus positive | 5 | 2 (40.0) | 1 (20.0) | 3 (60.0) |
| Enterovirus negative | 61 | 15 (24.6) | 12 (19.7) | 25 (41.0) |
| P‐value | 0.5 | 1.0 | 0.4 | |
| Human metapneumovirus positive | 1 | 0 | 0 | 1 (100) |
| Human metapneumovirus negative | 64 | 17 (26.6) | 13 (20.3) | 27 (41.5) |
| P‐value | 0.6 | 0.6 | 0.2 |
Number and percentage (between brackets) of samples in which both a virus and bacteria was detected. P‐value as determined using chi‐square analyses. Percentage calculated as percentage of the virus positive and virus negative value.
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