Table V.
Patient | Age/Sex | Underlying medical condition | Related treatment & complications | Virus | No. Samples | No. Weeks | Clinical Course |
---|---|---|---|---|---|---|---|
1 | 11 years, female | Beta thalassemia | URCB‐HSCT, GVHD | Norovirus GII | 6 | 25 | Diarrhea, cramping abdominal pain, emesis January – April 2007, new onset diarrhea, abdominal pain in July 2007 |
2 | 2 years, male | Severe infantile osteoporosis | URB‐HCST, GVHD | Norovirus GII | 4 | 32 | Symptomatic gastroenteritis October 2006 – May 2007 with failure to thrive |
3 | 5 months, female | Severe combined immunodeficiency | Bone marrow transplants (2) | Norovirus GII | 2 | 5 | Hospitalized May 2008 – August 2009 with persistent diarrhea, intermittent adenovirus, rotavirus, and norovirus GII positive samples; 2 consecutive norovirus GII samples |
4 | 6 years, male | Severe aplastic anemia | URCB‐HCST | Norovirus GII | 2 | 18 | Diarrhea, emesis March 2007; recurrent diarrhea in July 2007 |
5 | 20 months, male | Atypical rhabdoid tumor | Chemotherapy, multiple ASCTs | Astrovirus | 4 | 12 | Chemotherapy associated diarrhea and emesis, requiring multiple admissions, one episode associated with hypovolemic shock |
URCB‐HSCT, unrelated cord blood hematopoietic stem cell transplant; GVHD, graft‐versus‐host disease; AGE: acute gastroenteritis; ASCT, autologous stem cell transplant.