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. 2015 Mar 16;87(6):931–939. doi: 10.1002/jmv.24022

Table V.

Duration of Viral Shedding in Consecutive Stool Samples in Five Immunocompromised Hosts

Patient Age/Sex Underlying medical condition Related treatment & complications Virus No. Samples No. Weeks Clinical Course
1 11 years, female Beta thalassemia URCB‐HSCT, GVHD Norovirus GII 6 25 Diarrhea, cramping abdominal pain, emesis January – April 2007, new onset diarrhea, abdominal pain in July 2007
2 2 years, male Severe infantile osteoporosis URB‐HCST, GVHD Norovirus GII 4 32 Symptomatic gastroenteritis October 2006 – May 2007 with failure to thrive
3 5 months, female Severe combined immunodeficiency Bone marrow transplants (2) Norovirus GII 2 5 Hospitalized May 2008 – August 2009 with persistent diarrhea, intermittent adenovirus, rotavirus, and norovirus GII positive samples; 2 consecutive norovirus GII samples
4 6 years, male Severe aplastic anemia URCB‐HCST Norovirus GII 2 18 Diarrhea, emesis March 2007; recurrent diarrhea in July 2007
5 20 months, male Atypical rhabdoid tumor Chemotherapy, multiple ASCTs Astrovirus 4 12 Chemotherapy associated diarrhea and emesis, requiring multiple admissions, one episode associated with hypovolemic shock

URCB‐HSCT, unrelated cord blood hematopoietic stem cell transplant; GVHD, graft‐versus‐host disease; AGE: acute gastroenteritis; ASCT, autologous stem cell transplant.