Table 1.

Quantification of marker proteins in osteoclasts (expressed as mean pixel intensity per mm² cell area in arbitrary units assessed by immunocytochemistry and confocal microscopy) in cultures grown under modified pH conditions from day 7 to 14

Marker	Mean pixel intensity per mm2		% changes in mean pixel intensity	Significance
	pH 7.4	pH 6.8
VNR	19,818 ± 9,746	160,11 ± 10,324	−19	P = 0.032
TRAP	283,800 ± 115,287	108,863 ± 39,900	−61	P = 0.008
Proton pump	199,393 ± 124,358	595,057 ± 294,425	+298	P = 0.01
Cathepsin K	176,002 ± 91,707	5600,860 ± 107,428	+319	P = 0.001