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. 2019 Jun 13;91(9):1633–1642. doi: 10.1002/jmv.25502

Table 2.

Characteristics of hospitalized patients with SALRTI

Characteristics All SALRTI (%) a (n = 659) Any viral etiology (%) a (n = 326) Negative (%) a (n = 333) P value
Gender group
Male sex 417 (63.3) 202 (62.0) 215 (64.6) 0.489
Female sex 242 (36.7) 124 (38.0) 118 (35.4)
Age group
2 mo‐1 y 240 (36.4) 133 (40.8) 107 (32.1) 0.006
1‐3 y 160 (24.3) 87 (26.7) 73 (21.9)
3‐5 y 145 (22.0) 66 (20.2) 79 (23.7)
5‐10 y 70 (10.6) 27 (8.28) 43 (12.9)
10‐14 y 44 (6.7) 13 (4.0) 31 (9.3)
Clinical history and physical examination
T ≥ 38.0°C 622 (94.4) 303 (92.9) 319 (95.8) 0.112
Cough 630 (95.6) 310 (95.1) 320 (96.1) 0.530
Runny nose 165 (25.0) 102 (31.3) 63 (18.9) <0.001
Sore throat 46 (7.0) 28 (8.6) 18 (5.4) 0.109
Sputum production 404 (61.3) 220 (67.5) 184 (55.3) 0.001
Tachypnea 262 (39.8) 158 (48.5) 104 (31.2) <0.001
Difficulty breathing 411 (62.4) 234 (71.8) 177 (53.2) <0.001
Wheezing 207 (31.4) 148 (45.4) 59 (17.7) <0.001
Radiographic evidence of pneumonia 507 (76.9) 252 (77.3) 255 (76.6) 0.825
Lung rale sounds on auscultation 460 (69.8) 220 (67.5) 240 (72.1) 0.200
Comorbid conditions
Asthma 36 (5.5) 27 (8.3) 9 (2.7) 0.002
Heart failure 51 (7.7) 35 (10.7) 16 (4.8) 0.004
Hematological disease 63 (9.6) 32 (9.8) 31 (9.3) 0.825
Neuromuscular disease 5 (0.8) 3 (0.9) 2 (0.6) 0.683
Autoimmune disease 42 (6.4) 23 (7.1) 19 (5.7) 0.478
Immunosuppression 138 (20.9) 78 (23.9) 60 (18.0) 0.062
APACHE II score mean (SD) 14.1 (4.3) b 14.5 (4.6) b 13.9 (3.9) b <0.001
Presenting clinical manifestations
Noninvasive mechanical ventilation 170 (25.8) 92 (28.2) 78 (23.4) 0.159
Mechanical ventilation 189 (28.7) 103 (31.6) 86 (25.8) 0.102
Vasoactive drugs 177 (26.9) 89 (27.3) 88 (26.4) 0.800
Continuous venovenous hemofiltration 18 (2.7) 7 (2.1) 11 (3.3) 0.363
Corticoids 206 (31.3) 119 (36.5) 87 (26.1) 0.004

Abbreviations: APACHE II, Acute Physiology and Chronic Health Evaluation II; SALRTI, severe acute lower respiratory tract infection; SD, standard deviation.

a

Data is presented as no. (%) of patients unless otherwise indicated.

b

Values in brackets represent SD.

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