Table 2.
Characteristics | All SALRTI (%) a (n = 659) | Any viral etiology (%) a (n = 326) | Negative (%) a (n = 333) | P value |
---|---|---|---|---|
Gender group | ||||
Male sex | 417 (63.3) | 202 (62.0) | 215 (64.6) | 0.489 |
Female sex | 242 (36.7) | 124 (38.0) | 118 (35.4) | |
Age group | ||||
2 mo‐1 y | 240 (36.4) | 133 (40.8) | 107 (32.1) | 0.006 |
1‐3 y | 160 (24.3) | 87 (26.7) | 73 (21.9) | |
3‐5 y | 145 (22.0) | 66 (20.2) | 79 (23.7) | |
5‐10 y | 70 (10.6) | 27 (8.28) | 43 (12.9) | |
10‐14 y | 44 (6.7) | 13 (4.0) | 31 (9.3) | |
Clinical history and physical examination | ||||
T ≥ 38.0°C | 622 (94.4) | 303 (92.9) | 319 (95.8) | 0.112 |
Cough | 630 (95.6) | 310 (95.1) | 320 (96.1) | 0.530 |
Runny nose | 165 (25.0) | 102 (31.3) | 63 (18.9) | <0.001 |
Sore throat | 46 (7.0) | 28 (8.6) | 18 (5.4) | 0.109 |
Sputum production | 404 (61.3) | 220 (67.5) | 184 (55.3) | 0.001 |
Tachypnea | 262 (39.8) | 158 (48.5) | 104 (31.2) | <0.001 |
Difficulty breathing | 411 (62.4) | 234 (71.8) | 177 (53.2) | <0.001 |
Wheezing | 207 (31.4) | 148 (45.4) | 59 (17.7) | <0.001 |
Radiographic evidence of pneumonia | 507 (76.9) | 252 (77.3) | 255 (76.6) | 0.825 |
Lung rale sounds on auscultation | 460 (69.8) | 220 (67.5) | 240 (72.1) | 0.200 |
Comorbid conditions | ||||
Asthma | 36 (5.5) | 27 (8.3) | 9 (2.7) | 0.002 |
Heart failure | 51 (7.7) | 35 (10.7) | 16 (4.8) | 0.004 |
Hematological disease | 63 (9.6) | 32 (9.8) | 31 (9.3) | 0.825 |
Neuromuscular disease | 5 (0.8) | 3 (0.9) | 2 (0.6) | 0.683 |
Autoimmune disease | 42 (6.4) | 23 (7.1) | 19 (5.7) | 0.478 |
Immunosuppression | 138 (20.9) | 78 (23.9) | 60 (18.0) | 0.062 |
APACHE II score mean (SD) | 14.1 (4.3) b | 14.5 (4.6) b | 13.9 (3.9) b | <0.001 |
Presenting clinical manifestations | ||||
Noninvasive mechanical ventilation | 170 (25.8) | 92 (28.2) | 78 (23.4) | 0.159 |
Mechanical ventilation | 189 (28.7) | 103 (31.6) | 86 (25.8) | 0.102 |
Vasoactive drugs | 177 (26.9) | 89 (27.3) | 88 (26.4) | 0.800 |
Continuous venovenous hemofiltration | 18 (2.7) | 7 (2.1) | 11 (3.3) | 0.363 |
Corticoids | 206 (31.3) | 119 (36.5) | 87 (26.1) | 0.004 |
Abbreviations: APACHE II, Acute Physiology and Chronic Health Evaluation II; SALRTI, severe acute lower respiratory tract infection; SD, standard deviation.
Data is presented as no. (%) of patients unless otherwise indicated.
Values in brackets represent SD.
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