Table II.
Laboratory Data of Patients With Dengue and Control Subjects
| Classification | ||||
|---|---|---|---|---|
| Controls (n = 10) | Dengue without warning signs (n = 27) | Dengue with warning signs (n = 20) | Severe dengue (n = 15) | |
| Laboratory parameters | ||||
| Platelets × 103/mm3 (mean ± SD) | 296.8 ± 34.9a | 128 ± 73.7 | 88.2 ± 64.8b | 61.4 ± 48.1c , d |
| Hematocrit % (mean ± SD) | 39.9 ± 3.0 | 40.5 ± 3.8 | 39 ± 4.7 | 37.3 ± 4.4c |
| AST (IU/L) (mean ± SD) | — | 64.3 ± 63.9 | 80.2 ± 78.3 | 1592.3 ± 545.6c |
| ALT (IU/L) (mean ± SD) | — | 56.6 ± 48.8 | 71.5 ± 69.2 | 2055.0 ± 6791.0c |
| Leukocyte count/mm3 (mean ± SD) | 6073.0 ± 635.2 | 4130.0 ± 2148.0 | 4318.0 ± 2470.0 | 5813.0 ± 3545.0 |
| Lymphocyte count/mm3 (mean ± SD) | 1845.3 ± 349.3 | 1469.0 ± 993.0 | 1694.0 ± 1515.0 | 2253.0 ± 1591.0 |
| Monocyte count/mm3 (mean ± SD) | 432.7 ± 99.8 | 518.9 ± 377.8 | 409.7 ± 240.9 | 606.8 ± 387.0 |
| Monocyte % (mean ± SD) | 7.8 ± 1.7a | 12.3 ± 4.5 | 9.8 ± 4.0 | 12.7 ± 6.0 |
| Total lymphocyte % (mean ± SD) | 30.8 ± 7.6 | 36.0 ± 16.8 | 35.3 ± 17.0 | 43.8 ± 16.8 |
| CD14+ monocyte count/mm3 (mean ± SD) | 263.9.8 ± 35.7 | 254.5 ± 226.6 | 236.6 ± 136.7 | 317.4 ± 265.6 |
| CD4+ T lymphocyte count/mm3 (mean ± SD) | 616.2 ± 113.4a | 296.8 ± 192.5 | 500.7 ± 438.7 | 690.0 ± 486.0 |
| CD8+ T lymphocyte count/mm3 (mean ± SD) | 428.9 ± 205.5a | 199.1 ± 181.2 | 512.6 ± 331.7 | 345.2 ± 308.6 |
| CD14+ monocyte % (mean ± SD) | 60.8 ± 11.5 | 60.0 ± 21.1 | 57.0 ± 17.9 | 53.3 ± 18.9 |
| CD4+ T lymphocyte % (mean ± SD) | 30.2 ± 10.0 | 33.0 ± 14.3 | 31.7 ± 11.8 | 32.8 ± 12.1 |
| CD8+ T lymphocyte % (mean ± SD) | 19.9 ± 4.4 | 20.8 ± 9.3 | 20.7 ± 8.9 | 17.4 ± 8.0 |
Note SD, standard deviation; AST, aspartate transaminase; ALT, alanine transaminase.
Statistical differences were assessed by the Mann–Whitney test.
a
P values <0.05 of controls versus group(s) of patients with dengue.
b
Dengue without warning signs versus dengue with warning signs.
c
Dengue without warning signs versus severe dengue.
d
Dengue with warning signs versus severe dengue.