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. 2020 Apr 19;6(2):00270-2019. doi: 10.1183/23120541.00270-2019

TABLE 3.

Observed frequencies for each admission for management of acute exacerbation of COPD according to COPD-X guideline recommendations

Category COPD-X guideline recommendation (version 2.34, November 2012) All sites (N=207) Site 1 (N=65) Site 2 (N=8) Site 3 (N=39) Site 4 (N=65) Site 5 (N=30) p-value
Confirm exacerbation and categorise severity “Unless confused or comatose, even the sickest of patients can perform an FEV1 manoeuvre” [p. 61]
FEV1 performed this admission/patients admitted
45/198 (22.7%) 1/65 (1.5%) 0/5 (0%) 2/38 (5.3%) 33/62 (53.2%) 9/28 (32.1%) <0.001
“Arterial blood gas levels should be measured if the FEV1 is less than 1.0 L or less than 40% predicted” [p. 61]
ABG or VBG taken/patients with any documented FEV1 <1 L
86/106 (81.1%) 23/31 (74.1%) 3/3 (100%) 8/13(61.5%) 43/46(93.5%) 9/13(69.2%) 0.017
“Chest x-ray…helps to identify alternative diagnoses and complications” [p. 61]
Chest radiography performed/patients admitted
203/204 (99.5%) 65/65 (100%) 7/8 (87.5%) 39/39 (100%) 62/62 (100%) 30/30 (100%) 0.039
Optimise treatment “Oral corticosteroids hasten resolution and reduce the likelihood of relapse” [p. 61]
Prescribed corticosteroids/patients admitted
195/205 (95.1%) 65/65 (100%) 7/7 (100%) 37/39 (94.2%) 59/64 (92.2%) 27/30 (90%) 0.085
“Antibiotics are given for purulent sputum to cover for typical and atypical organisms” [p. 61]
Antibiotics prescribed/patients with change in sputum colour
95/100 (95.0%) 30/32 (93.8%) 2/3 (66.7%) 14/15 (93.3%) 35/35 (100%) 14/15 (93.3%) 0.085
“Oxygen therapy…indicated in patients with hypoxia… minimise excessive oxygen administration” [p. 61]
All patients who were administered oxygen therapy/patients admitted
180/202 (89.1%) 52/65 (80.0%) 8/8 (100%) 32/36 (88.9%) 61/63 (96.8%) 27/30 (90.0%) 0.034
“Oxygen therapy…indicated in patients with hypoxia… minimise excessive oxygen administration” [p. 61]
Patients who were administered oxygen therapy when PaO2 <80 mmHg and ABG taken on air this admission/all patients who had PaO2 <80 mmHg when ABG taken on air this admission
25/27 (92.6%) 5/7 (71.4%) 0/0 (0%) 1/1 (100%) 13/13 (100%) 6/6 (100%) 0.177
“Ventilatory assistance… indicated for increasing hypercapnia and acidosis” [p. 61]
Received ventilatory assistance/those with pH <7.35
21/32 (65.6%) 6/8 (75%) 0/2 (0%) 4/6 (66.7%) 9/14 (64.3%) 2/2 (100%) 0.429
Refer appropriately to prevent further deterioration “Pulmonary rehabilitation…can be initiated immediately following an acute exacerbation” [p. 66]
Referred to pulmonary rehabilitation/patients admitted
60/185 (32.4%) 33/46 (71.7%) 3/8 (37.5%) 4/39 (10.3%) 14/64 (21.9%) 6/28 (21.4%) <0.001
“It is recommended that the first review after a hospital admission should be by the GP and within seven days of discharge” [p. 67]
Referred to GP/patients admitted
136/177 (76.8%) 43/47 (91.5%) 1/6 (16.7%) 23/34 (67.7%) 39/60 (65.0%) 30/30 (100%) <0.001

Data calculated on individual admissions (n=207); % are for documented values (unrecorded, unknown and undocumented values have been treated as missing values). FEV1: forced expiratory volume in 1 s; ABG: arterial blood gas; VBG: venous blood gas; PaO2: arterial oxygen tension; GP: general practitioner.