Table 3.
Diagnostic value of patient characteristics, presenting symptoms and additional testing in adult acute cough patients in primary care that tested positive for respiratory syncytial virus (RSV) or influenza virus.
| RSV – adjusted OR (95% CI) | Influenza A – adjusted OR (95% CI) | Influenza B – adjusted OR (95% CI) | |
|---|---|---|---|
| Gender: male | 0.78 [0.54–1.12] | 0.96 [0.68–1.34] | 1.28 [0.85–1.94] |
| Current smoker | 0.82 [0.53–1.25] | 0.60 [0.40–0.89] | 0.80 [0.50–1.30] |
| History of pulmonary comorbiditiesa | 1.14 [0.73–1.78] | 1.16 [0.74–1.82] | 0.55 [0.27–1.13] |
| History of cardiac comorbiditiesb | 0.94 [0.52–1.71] | 0.64 [0.29–1.44] | 1.24 [0.55–2.78] |
| Presence of runny nose | 2.42 [1.54–3.78] | 1.36 [0.93–1.98] | 1.35 [0.85–2.16] |
| Presence of fever | 0.93 [0.64–1.36] | 4.23 [2.95–6.07] | 3.71 [2.37–5.79] |
| Presence of wheezing | 1.24 [0.87–1.75] | 1.21 [0.85–1.73] | 0.72 [0.44–1.16] |
| Interference with normal activities or work | 1.10 [0.76–1.58] | 1.65 [1.12–2.44] | 2.76 [1.59–4.78] |
| Pneumonia detected | 0.50 [0.18–1.39] | 0.85 [0.38–1.91] | 0.34 [0.08–1.42] |
| Bacteria detected | 0.89 [0.58–1.37] | 1.05 [0.71–1.56] | 1.36 [0.85–2.16] |
| Other viruses detected | 0.18 [0.12–0.29] | 0.17 [0.11–0.26] | 0.10 [0.06–0.19] |
OR: odds ratio; CI: (Wald) confidence interval; numbers printed in bold indicate significance: models accounted for significant covariates (influenza vaccination, smoking status, days coughing prior to consultation and presence of other viruses for RSV; history of cardiac comorbidities, influenza vaccination, smoking status, days coughing prior to consultation and presence of other viruses for influenza A; history of pulmonary comorbidities, influenza vaccination, days coughing prior to consultation and presence of other viruses for influenza B).
Pulmonary comorbidities include asthma, chronic obstructive pulmonary disease and other chronic lung diseases.
Cardiac comorbidities include heart failure, ischemic heart disease and other heart diseases.