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Superposition of SARS-CoV and SARS-CoV-2 spike proteins highlighting the spike–ACE2 interface binding pocket. Zoom in at the residues of SARS-CoV-2 spike S1 Asn167, Tyr169, Tyr133, Tyr129, Gln178, Phe166, Leu135 and Gln173 and the correspondent SARS-CoV spike S1 Asn473, Tyr475, Tyr440, Tyr436, Tyr484, Leu472, Tyr442 and Asn479.
