Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Drug sensitivity against recombinant EV-D68 US/MO/14–18947 viruses
| R856932 | Pleconaril | |||
|---|---|---|---|---|
| CPE EC50 (μM) | PRA EC50 (μM) | CPE EC50 (μM) | PRA EC50 (μM) | |
| rMO WT | 0.86 ± 0.14 | 0.39 ± 0.03 | 0.07 ± 0.02 | 0.03 ± 0.01 |
| rMO VP1-A129V | 16.6 ± 1.2 | 16.0 ± 7.4 | 0.44 ± 0.04 | 0.23 ± 0.04 |
| rMO VP2-T139A | 1.46 ± 0.39 | 1.15 ± 0.14 | 0.13 ± 0.05 | 0.13 ± 0.02 |
CPE: cytopathic effect assay; PRA: Plaque reduction assay; EC50 (μM) = mean ± standard deviation. The values are the mean ± standard deviation from three replicates.
