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. 2020 Apr 15;13:1091–1104. doi: 10.2147/IDR.S191387

Table 3.

Reported Cases of Osteoarticular Infections with Raoultella ornithinolytica

Authors Year Age (Yr) Sex Comorbidities Diagnosis Positive Sample Identification Technique Antimicrobial Susceptibility Treatment
Zheng et al57 2015 13 M Wound infection (post-ORIF) Wound fluid 16S rRNA gene sequencing S: Ciprofloxacin, piperacillin/tazobactam
R: Amikacin, ceftriaxone, imipenem, ertapenem, aztreonam, tobramycin, ceftazidime, gentamicin, ampicillin/sulbactam, cefepime
Debridement/drainage, trimethoprim/sulfamethoxazole
Venus et al70 2016 68 F Sickle cell disease Septic arthritis of the knee Articular fluid MALDI-TOF S: Amoxicillin/clavulanate, cefazolin, ceftriaxone, ciprofloxacin, gentamicin, trimethoprim/sulfamethoxazole Knee irrigation and debridement IV cefazolin (2 weeks) then oral ciprofloxacin (2 weeks)
Treated breast cancer
Seng et al69 2016 67 M COPD Prosthetic joint infection Periprosthetic effusion MALDI-TOF S: Amoxicillin/clavulanate, ticarcillin/clavulanate, ceftriaxone, ciprofloxacin, doxycycline, aminoglycosides, cotrimoxazole



R: Amoxicillin, rifampin
Prosthetic exchange IV ceftriaxone (1 month) and oral ciprofloxacin, then oral doxycycline and ciprofloxacin
Peripheral artery disease 16s rRNA gene sequencing
Hypertension
Bilateral hip prosthesis
Plate osteosynthesis of a periprosthetic femur fracture
Levorova et al5 2017 38 F - Septic arthritis of the temporomandibular joint Articular fluid Not specified S: Amoxicillin/clavulanate, ampicillin/sulbactam, sulbactam, ciprofloxacin, cotrimoxazole, cefuroxime Arthrocentesis Amoxicillin and amoxicillin/clavulanate
Lam et al6 2018 85 M Emphysema Mandibular osteomyelitis Aspirate of the abscess MALDI-TOF S: Ciprofloxacin, trimethoprim/sulfamethoxazole, cefotaxime, piperacillin/tazobactam

I: Cefazolin
Piperacillin/tazobactam (4 days) then amoxicillin/clavulanate (total of 1 month) then trimethoprim/sulfamethoxazole (2 months)
Hypertension
Dyslipidemia
Molar extraction

Abbreviations: Yr, years; M, male; F, female; COPD, chronic obstructive pulmonary disease; ORIF, open reduction and internal fixation; rRNA, ribosomal RNA; MALDI-TOF MS, matrix assisted laser desorption ionization-time of flight mass spectrometry; S, susceptible; R, resistant; I, intermediate.