Table 3.
Authors | Year | Age (Yr) | Sex | Comorbidities | Diagnosis | Positive Sample | Identification Technique | Antimicrobial Susceptibility | Treatment | |
---|---|---|---|---|---|---|---|---|---|---|
Zheng et al57 | 2015 | 13 | M | – | Wound infection (post-ORIF) | Wound fluid | 16S rRNA gene sequencing | S: Ciprofloxacin, piperacillin/tazobactam R: Amikacin, ceftriaxone, imipenem, ertapenem, aztreonam, tobramycin, ceftazidime, gentamicin, ampicillin/sulbactam, cefepime |
Debridement/drainage, trimethoprim/sulfamethoxazole | |
Venus et al70 | 2016 | 68 | F | Sickle cell disease | Septic arthritis of the knee | Articular fluid | MALDI-TOF | S: Amoxicillin/clavulanate, cefazolin, ceftriaxone, ciprofloxacin, gentamicin, trimethoprim/sulfamethoxazole | Knee irrigation and debridement | IV cefazolin (2 weeks) then oral ciprofloxacin (2 weeks) |
Treated breast cancer | ||||||||||
Seng et al69 | 2016 | 67 | M | COPD | Prosthetic joint infection | Periprosthetic effusion | MALDI-TOF | S: Amoxicillin/clavulanate, ticarcillin/clavulanate, ceftriaxone, ciprofloxacin, doxycycline, aminoglycosides, cotrimoxazole R: Amoxicillin, rifampin |
Prosthetic exchange | IV ceftriaxone (1 month) and oral ciprofloxacin, then oral doxycycline and ciprofloxacin |
Peripheral artery disease | 16s rRNA gene sequencing | |||||||||
Hypertension | ||||||||||
Bilateral hip prosthesis | ||||||||||
Plate osteosynthesis of a periprosthetic femur fracture | ||||||||||
Levorova et al5 | 2017 | 38 | F | - | Septic arthritis of the temporomandibular joint | Articular fluid | Not specified | S: Amoxicillin/clavulanate, ampicillin/sulbactam, sulbactam, ciprofloxacin, cotrimoxazole, cefuroxime | Arthrocentesis | Amoxicillin and amoxicillin/clavulanate |
Lam et al6 | 2018 | 85 | M | Emphysema | Mandibular osteomyelitis | Aspirate of the abscess | MALDI-TOF | S: Ciprofloxacin, trimethoprim/sulfamethoxazole, cefotaxime, piperacillin/tazobactam I: Cefazolin |
Piperacillin/tazobactam (4 days) then amoxicillin/clavulanate (total of 1 month) then trimethoprim/sulfamethoxazole (2 months) | |
Hypertension | ||||||||||
Dyslipidemia | ||||||||||
Molar extraction |
Abbreviations: Yr, years; M, male; F, female; COPD, chronic obstructive pulmonary disease; ORIF, open reduction and internal fixation; rRNA, ribosomal RNA; MALDI-TOF MS, matrix assisted laser desorption ionization-time of flight mass spectrometry; S, susceptible; R, resistant; I, intermediate.