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. 2020 Apr 15;12:2549–2557. doi: 10.2147/CMAR.S238492

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© 2020 Li et al.

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Comparison of the miRNA expression levels in cancerous and normal tissues. The results showed that miR-145, miR-23b, miR-204, miR-195, miR-23a, miR-497, miR-429, and the miRNA panel were significantly dysregulated (P<0.05)(A–H); ROC analysis demonstrated that miR-145, miR-23b, miR-195, and the miRNA panel could detect, with a high AUC value, patients with CRC. Regarding miR-204, miR-23a, miR-497, and miR-429, although they caused significant dysregulation, their sensitivity, specificity, and AUC values were unsatisfactory (I–K).