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. 2020 Apr 15;12:2549–2557. doi: 10.2147/CMAR.S238492

Table 1.

Expression Levels of 20 miRNAs in Cancer Samples Compared with Those in Normal Controls by Paired t-Test. Compared with the Adjacent Normal Samples, in the Cancer Tissues, 7 of the 20 Selected miRNAs Were Significantly Dysregulated (P<0.05), and Were Likely to Be Good Candidates as Diagnostic Biomarkers. The Fold Changes in All the Dysregulated miRNAs Were Greater Than 2-Fold, Upregulated or Downregulated. Furthermore, miR-145 Demonstrated the Greatest Change at More Than 16-Fold

miRNA ΔΔCt 2^-ΔΔCt Fold Change P-value miRNA ΔΔCt 2^-ΔΔCt Fold Change P-value
miR-145 4.010 0.062 −16.111 <0.001 miR-15a 0.117 0.922 −1.085 0.763
miR-23b 2.245 0.211 −4.740 <0.001 miR-489 −0.089 1.064 1.064 0.878
miR-204 1.598 0.330 −3.027 0.000 miR-425 −0.178 1.131 1.131 0.700
miR-195 1.398 0.379 −2.635 0.002 miR-216a −0.248 1.188 1.188 0.702
miR-23a 1.352 0.392 −2.553 0.002 miR-200b −0.306 1.236 1.236 0.523
miR-497 1.133 0.456 −2.193 0.018 miR-424 −0.360 1.284 1.284 0.351
miR-23c 0.838 0.559 −1.788 0.128 miR-200c −0.400 1.320 1.320 0.320
miR-15b 0.655 0.635 −1.574 0.136 miR-503 −0.527 1.441 1.441 0.127
miR-16 0.373 0.772 −1.295 0.352 miR-211 −0.531 1.445 1.445 0.544
miR-216b 0.246 0.843 −1.186 0.652 miR-429 −1.825 3.543 3.543 <0.001