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. 2020 Apr 20;7:19. doi: 10.1186/s40779-020-00247-7

Table 3.

Different heparin anticoagulant doses determined by the risk of bleeding

Loading dose (IU/kg) Maintenance dose IU/(kg∙h) INR APTT (s) PLT (×109/L)
30 ~ 50 10 ≤ 1.5 ≤ 40 ≥ 150
20–40 5 > 1.5 but ≤2.5 > 40 but ≤60 < 150 but ≥70
No Citrate anticoagulation or no anticoagulation > 2.5 > 60 < 70