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. Author manuscript; available in PMC: 2021 Apr 1.
Published in final edited form as: Eur J Neurosci. 2020 Jan 20;51(7):1624–1641. doi: 10.1111/ejn.14669

Figure 2.

Figure 2.

Trajectories of E/I ratio and total current values for networks with additional parameter changes addressing aspects of biological realism display the same qualitative behavior. Comparing with Figure 1b, the value of one parameter is changed in each panel while other parameters stay the same as original simulation. Inhibitory weight wI is adjusted accordingly to show the appropriate E/I ratio range. a) random network with increased connectivity density (20% vs 3%, wI=0.2mS/cm2); b) 80% excitatory cells and 20% inhibitory cells (wI=2.8mS/cm2); c) different values for the four types of synapses, wEE is varied, wEI = 0.35mS/cm2, wIE = 0.5mS/ cm2, wII = 0.7 mS/ cm2; d) same as panel e) but the values for wEI and wIE are reversed: wEI = 0.5mS/ cm2, wIE = 0.35mS/ cm2, wII = 0.7 mS/cm2.