TABLE 2.
Analysis of single nucleotide polymorphisms using whole-genome sequencing data
| Relative position in genomea | Gene | Refb | SNP |
Alteration of amino acidc | Type of mutationd | ||||
|---|---|---|---|---|---|---|---|---|---|
| WT 1030 | WT 1031 | WT 1032 | WT 1033 | EGDe ΔflaA | |||||
| 188308 | lmo0184 | G | T | —e | — | T | — | 148 E to stop codon | Nonsense |
| 189757 | lmo0185 | C | A | — | — | — | — | — | Synonymous |
| 264578 | lmo0247 | G | T | T | T | T | T | — | Synonymous |
| 280225 | rpoC | C | G | — | — | — | — | 1166 I to M | Missense |
| 435968 | Intergenic | C | A | A | A | A | A | Intergenic | Intergenic |
| 929469 | rsbU | C | CTT | — | — | CTT | — | 245 L to F, frameshift | Nonsense |
| 1116367 | lmo1081 (rmlA) | G | T | — | — | — | — | 241 E to stop codon | Nonsense |
| 1442124 | Intergenic | C | A | A | A | A | A | Intergenic | Intergenic |
| 1890030 | lmo1814 | C | A | — | — | A | — | 82 G to W | Missense |
| 2003900 | aroF | C | A | — | — | — | — | 138 V to F | Missense |
| 2207164 | lmo2125 | T | G | — | — | — | — | 400 Q to P | Missense |
| 2734614 | lmo2660 | C | A | — | — | — | — | 211 G to V | Missense |
| 2836724 | lmo2757 | G | — | — | A | — | — | 354 R to C | Missense |
| 2849710 | lmo2769 | G | — | — | — | T | — | 247 Y to stop codon | Nonsense |
| 2943565 | Intergenic | G | T | T | T | T | T | Intergenic | Intergenic |
a
The relative locations of the SNPs present in the strains are compared with NC_003210.
b
Ref, nucleotide present at the corresponding relative position in NC_003210.
c
The codons of the coding sequences with SNPs were analyzed by ExPASy translation tool followed by BLAST with the original amino acid sequences.
d
SNPs were categorized as intergenic, synonymous, missense, or nonsense.
e
—, no difference from the reference genome.