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. 2020 Mar 26;37:100981. doi: 10.1016/j.molmet.2020.100981

Figure 2.

Figure 2

Hepatic steatosis in LivCox10−/−livers after influenza infection. (A) Representative EMs of livers isolated from uninfected mice (left column) or after PR8 infection (right column). Black arrows indicate mitochondria. White arrows indicate lipid. N: nucleus. Scale bar = 1 μm. N = 4 mice/group. Data are representative of three experiments. (B) Representative ORO stains of liver tissue prepared from uninfected (right column) or PR8-infected mice. Scale bar = 50 μm. N = 4 mice/group. Data are representative of three experiments. (C) Expression of PPARα protein in lysates prepared from liver tissue harvested from uninfected (solid circles) or PR8-infected (open circles) LivCox10+/+ and LivCox10−/− mice. N = 3–4 mice/group. (D) Expression of ACADVL (top) and HADHA (bottom) proteins in liver lysates. N = 3–4 mice/group. (E) Heatmap of z-scores from acylcarnitine analyses of livers. N = 8 mice/group. Data represent mean ± SEM. ∗P < 0.05, ∗∗P < 0.01, and ∗∗∗P < 0.001.