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. Author manuscript; available in PMC: 2020 Apr 20.
Published in final edited form as: J Pharmacokinet Pharmacodyn. 2018 Apr 27;45(4):557–575. doi: 10.1007/s10928-018-9585-x

Fig. 4.

Fig. 4

Hepatic C/EBP-β mRNA (top left panel), PEPCK mRNA (middle left panel), PEPCK protein (middle right panel), plasma glucose (bottom left panel), and plasma insulin (bottom right panel) dynamics after 50 mg/kg MPL. The circles and bars are means + 1 SD and solid lines depict model (Fig. 1) fitting results based on the parameters shown in Tables 1 and 3