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. Author manuscript; available in PMC: 2020 Apr 20.
Published in final edited form as: J Pharmacokinet Pharmacodyn. 2018 Apr 27;45(4):557–575. doi: 10.1007/s10928-018-9585-x

Fig. 5.

Fig. 5

Hepatic STAT3 mRNA (top left panel), STAT3 protein (top right panel), Serpin A1 protein (middle left panel), Serpin A3n (middle right panel), and blood lymphocyte (bottom left panel) dynamics after 50 mg/kg MPL. The circles and bars are means + 1 SD and solid lines depict model (Fig. 1) fitting results based on the parameters shown in Tables 1 and 4