Table 1(a).
Most up- and down-regulated genes in TSA treated MV4-11
|
Gene Bank
Accession |
Gene symbol | Gene description ( Homo sapiens) |
*Folds
Change |
|---|---|---|---|
| NM_001082 | CYP4F2 | Cytochrome P450, family 4, subfamily F, polypeptide 2 | 1094.05 |
| NM_014971 | EFR3B | EFR3 homolog B (S. cerevisiae) | 360.59 |
| NM_006569 | CGREF1 | Cell growth regulator with EF-hand domain 1 | 348.85 |
| NM_017702 | DEF8 | Differentially expressed in FDCP 8 | 325.92 |
| NM_003914 | CCNA1 | Cyclin A1 | 298.44 |
| NM_003255 | TIMP2 | TIMP metallopeptidase inhibitor 2 | 281.56 |
| NM_031313 | ALPPL2 | Alkaline phosphatase, placental-like 2 | 250.36 |
| NM_032704 | TUBA1C | Tubulin, alpha 1c | 234.14 |
| NM_003955 | SOCS3 | Suppressor of cytokine signaling 3 | 176.76 |
| NM_001204054 | NDUFC2 | NADH dehydrogenase (ubiquinone) 1, subcomplex unknown 2 | 166.94 |
| NR_027028 | GUSBP1 | Glucuronidase, beta pseudogene 1 | 153.18 |
| NM_004522 | KIF5C | Kinesin family member 5C | 153.59 |
| NM_003520 | HIST1H2BN | Histone cluster 1, H2bn | 150.13 |
| NM_006321 | ARIH2 | Ariadne RBR E3 ubiquitin protein ligase 2 | 133.61 |
| NM_000612 | IGF2 | Insulin-like growth factor 2 | 131.09 |
| NM_177424 | STX12 | Syntaxin 12 | 103.73 |
| NM_006086 | TUBB3 | Tubulin, beta 3 class III | 80.38 |
| NM_004672 | MAP3K6 | Mitogen-activated protein kinase kinase kinase 6 | 39.50 |
| NM_001025300 | RAB12 | member RAS oncogene family | 38.83 |
| NM_139314 | ANGPTL4 | Angiopoietin-like 4 | 26.79 |
| NM_018437 | HEMGN | Hemogen | -518.75 |
| NM_024913 | CPED1 | Cadherin-like and PC-esterase domain containing 1 | -243.96 |
| NM_003152 | STAT5A | Signal transducer and activator of transcription 5A | -159.83 |
| NM_002838 | PTPRC | Protein tyrosine phosphatase, receptor type C | -138.75 |
| NM_080612 | GAB3 | GRB2-associated binding protein 3 | -117.26 |
| NM_003126 | SPTA1 | Spectrin, alpha, erythrocytic 1 | -107.30 |
| NM_015401 | HDAC7 | Histone deacetylase 7 | -88.16 |
| NM_006563 | KLF1 | Kruppel-like factor 1 (erythroid) | -85.08 |
| NM_015660 | GIMAP2 | GTPase, IMAP family member 2 | -73.83 |
| NM_006163 | NFE2 | Nuclear factor, erythroid 2 | -69.24 |
| NM_213674 | TPM2 | Tropomyosin 2 (beta) | -57.76 |
| NM_006287 | TFPI | Tissue factor pathway inhibitor | -55.30 |
| NM_005021 | ENPP3 | pyrophosphatase/phosphodiesterase 3 | -49.49 |
| NM_004688 | NMI | N-myc (and STAT) interactor | -47.85 |
| NM_000037 | ANK1 | Ankyrin 1, erythrocytic, transcript variant 3 | -46.78 |
| NM_013427 | ARHGAP6 | Rho GTPase activating protein 6 | -42.54 |
| NM_006546 | IGF2BP1 | Insulin-like growth factor 2 mRNA binding protein 1 | -42.54 |
| NM_033306 | CASP4 | Caspase 4, apoptosis-related cysteine peptidase | -42.42 |
| NM_080588 | PTPN7 | Protein tyrosine phosphatase, non-receptor type 7 | -39.69 |
| NM_004753 | DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -36.59 |
| NR_026812 | RUNX1-IT1 | RUNX1 intronic transcript 1 | -22.05 |
| NM_003153 | STAT6 | signal transducer and activator of transcription 6 | -10.04 |
*Folds-change of treatment group compared to control analyzed by Genespring software analysis, Moderated T-test, p<0.05)