Table 1(c).
Most up- and down-regulated genes in TSA+5-Aza treated MV4-11
| Gene Bank Accession | Gene symbol | Gene description ( Homo sapiens) |
*Folds
change |
|---|---|---|---|
| NM_001145191 | FAM200B | Family with sequence similarity 200, member B | 521.92 |
| NM_197958 | LARP6 | La ribonucleoprotein domain family, member 6 | 506.68 |
| NM_017702 | DEF8 | differentially expressed in FDCP 8 homolog | 268.16 |
| NR_027028 | GUSBP1 | Homo sapiens glucuronidase, beta pseudogene 1 | 243.94 |
| NM_032905 | RBM17 | RNA binding motif protein 17 | 160.05 |
| NM_014773 | KIAA0141 | KIAA0141 (KIAA0141) | 157.47 |
| NM_001204054 | NDUFC2 | NADH dehydrogenase (ubiquinone) 1, subcomplex unknown 2 | 155.54 |
| NM_016256 | NAGPA | N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase | 141.82 |
| NM_032704 | TUBA1C | tubulin, alpha 1c | 139.42 |
| NM_013268 | LGALS13 | lectin, galactoside-binding, soluble 13 | 132.17 |
| NM_004187 | KDM5C | lysine (K)-specific demethylase 5C | 116.85 |
| NM_024097 | C1orf50 | chromosome 1 open reading frame 50 | 113.21 |
| NM_006321 | ARIH2 | ariadne RBR E3 ubiquitin protein ligase 2 | 97.43 |
| NM_014035 | SNX24 | sorting nexin 24 | 94.35 |
| NM_000600 | IL6 | interleukin 6 (interferon, beta 2) | 91.55 |
| NM_138433 | KLHDC7B | kelch domain containing 7B | 89.54 |
| NM_033028 | BBS4 | Bardet-Biedl syndrome 4 | 87.94 |
| NM_177424 | STX12 | syntaxin 12 | 87.27 |
| NM_015046 | SETX | senataxin | 87.24 |
| NM_001031713 | MCUR1 | mitochondrial calcium uniporter regulator 1 | 85.70 |
| NM_001010893 | SLC10A5 | solute carrier family 10, member 5 | 79.58 |
| NM_031925 | TMEM120A | transmembrane protein 120A | 78.16 |
| NM_006945 | SPRR2D | small proline-rich protein 2D | 71.36 |
| NM_052936 | ATG4A | Homo sapiens autophagy related 4A, cysteine peptidase | 70.34 |
| NM_014945 | ABLIM3 | actin binding LIM protein family, member 3 | 68.78 |
| NM_015701 | ERLEC1 | endoplasmic reticulum lectin 1 | 61.29 |
| NM_004672 | MAP3K6 | mitogen-activated protein kinase kinase kinase 6 | 59.79 |
| NM_006415 | SPTLC1 | serine palmitoyltransferase, long chain base subunit 1 | 59.76 |
| NM_001025300 | RAB12 | RAB12, member RAS oncogene family | 59.16 |
| NM_005988 | SPRR2A | small proline-rich protein 2A | 58.97 |
| NM_001080541 | MGA | Homo sapiens MGA, MAX dimerization protein | 56.75 |
| NM_144569 | SPOCD1 | Homo sapiens SPOC domain containing 1 | 54.22 |
| NM_018357 | LARP6 | Homo sapiens La ribonucleoprotein domain family, member 6 | 54.17 |
| NM_206818 | OSCAR | osteoclast associated, immunoglobulin-like receptor | 53.30 |
| NM_017956 | TRMT12 | tRNA methyltransferase 12 homolog (S. cerevisiae) | 52.10 |
| NM_005614 | RHEB | Ras homolog enriched in brain | 50.16 |
| NM_012337 | CCDC19 | coiled-coil domain containing 19 | 50.03 |
| NM_014884 | SUGP2 | SURP and G patch domain containing 2 | 47.37 |
| NM_015335 | MED13L | mediator complex subunit 13-like | 47.11 |
| NM_173698 | FAM133A | family with sequence similarity 133, member A | -153.62 |
| NM_145290 | GPR125 | G protein-coupled receptor 125 | -78.33 |
| NM_017521 | FEV | Homo sapiens FEV | -77.72 |
| NM_001541 | HSPB2 | Homo sapiens heat shock 27kDa protein 2 | -67.21 |
| NM_032501 | ACSS1 | Homo sapiens acyl-CoA synthetase short-chain family member 1 | -63.80 |
| NM_021992 | TMSB15A | thymosin beta 15a | -55.18 |
| NM_012449 | STEAP1 | six transmembrane epithelial antigen of the prostate 1 | -44.93 |
| NM_017414 | USP18 | ubiquitin specific peptidase 18 | -44.70 |
| NM_001803 | CD52 | CD52 molecule | -44.63 |
| NM_004126 | GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | -42.81 |
| NM_000519 | HBD | hemoglobin, delta | -40.08 |
| NM_033258 | GNG8 | guanine nucleotide binding protein (G protein), gamma 8 | -38.65 |
| NM_138444 | KCTD12 | potassium channel tetramerization domain containing 12 | -35.88 |
| NM_002866 | RAB3A | RAB3A, member RAS oncogene family | -35.15 |
| NM_014697 | NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein | -35.11 |
| NM_018437 | HEMGN | hemogen | -34.39 |
| NM_207459] | TEX19 | testis expressed 19 | -33.52 |
| NM_004982 | KCNJ8 | potassium inwardly-rectifying channel, subfamily J, member 8 | -33.13 |
| NM_013251 | TAC3 | tachykinin 3 222335545766788WWSSF BBGTT | -30.44 |
| NM_032333 | FAM213A | family with sequence similarity 213, member A | -29.38 |
| NM_213599 | ANO5 | anoctamin 5 | -29.37 |
| NM_130776 | XAGE3 | X antigen family, member 3 | -28.64 |
| NM_002585 | PBX1 | pre-B-cell leukemia homeobox 1 | -28.42 |
| NM_001110199 | SRRM3 | Homo sapiens serine/arginine repetitive matrix 3 | -28.20 |
| NM_000537 | REN | renin | -27.47 |
*Folds-change of treatment group compared to control analyzed by Genespring software analysis, Moderated T-test, p<0.05)