Table 2(a).
Most up- and down-regulated genes in TSA treated Kasumi 1
| Gene Bank Accession | Gene symbol |
Gene description
( Homo sapiens) |
*Folds
change |
|---|---|---|---|
| NM_139314 | ANGPTL4 | angiopoietin-like 4 | 791.26 |
| NM_182908 | DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 612.16 |
| NM_001069 | TUBB2A | tubulin, beta 2A class IIa | 574.87 |
| NM_001080434 | LMTK3 | lemur tyrosine kinase 3 | 356.19 |
| NM_138345 | VWA5B2 | von Willebrand factor A domain containing 5B2 | 331.00 |
| NM_030630 | HID1 | HID1 domain containing | 331.00 |
| NM_006928 | PMEL | premelanosome protein | 323.68 |
| NM_145056 | DACT3 | dishevelled-binding antagonist of beta-catenin 3 | 269.03 |
| NM_144698 | ANKRD35 | ankyrin repeat domain 35, | 258.42 |
| NM_014971 | EFR3B | EFR3 homolog B (S. cerevisiae) | 248.79 |
| NM_004933 | CDH15 | cadherin 15, type 1, M-cadherin (myotubule) | 221.35 |
| NM_006086 | TUBB3 | tubulin, beta 3 class III | 205.73 |
| NM_000088 | COL1A1 | collagen, type I, alpha 1 | 122.33 |
| NM_017577 | GRAMD1C | GRAM domain containing 1C | 109.67 |
| NM_080860 | RSPH1 | radial spoke head 1 homolog | 109.55 |
| NM_003835 | RGS9 | regulator of G-protein signaling 9 | 103.85 |
| NM_001098722 | GNG4 | guanine nucleotide binding protein (G protein), gamma 4 | 102.41 |
| NM_005325 | HIST1H1A | histone cluster 1, H1a | 99.67 |
| NM_018667 | SMPD3 | sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) | 98.71 |
| NM_033103 | RHPN2 | rhophilin, Rho GTPase binding protein 2 | 91.75 |
| NM_007224 | NXPH4 | neurexophilin 4 | 88.57 |
| NM_014226 | MOK | MOK protein kinase | 73.56 |
| NM_001077621 | VPS37D | vacuolar protein sorting 37 homolog D | 69.03 |
| NM_001145028 | PALM3 | paralemmin 3 | 66.97 |
| NM_177403 | RAB7B | RAB7B, member RAS oncogene family | -264.07 |
| NM_005574 | LMO2 | Homo sapiens LIM domain only 2 (rhombotin-like 1) | -215.33 |
| NM_001004196 | CD200 | CD200 molecule | -162.39 |
| NM_001146 | ANGPT1 | angiopoietin 1 | -159.45 |
| NM_003474 | ADAM12 | ADAM metallopeptidase domain 12 | -137.13 |
| NM_003942 | RPS6KA4 | Homo sapiens ribosomal protein S6 kinase, 90kDa, polypeptide 4 | -136.39 |
| NM_080588 | PTPN7 | protein tyrosine phosphatase, non-receptor type 7 | -133.96 |
| NM_130782 | RGS18 | regulator of G-protein signaling 18 | -119.12 |
| NM_033101 | LGALS12 | lectin, galactoside-binding, soluble, 12 | -94.20 |
| NM_002005 | FES | FES proto-oncogene, tyrosine kinase | -93.71 |
| NM_080387 | CLEC4D | C-type lectin domain family 4, member D | -93.00 |
| NM_024888 | LPPR3 | lipid phosphate phosphatase-related protein type 3 | -80.70 |
| NM_012252 | TFEC | transcription factor EC | -77.90 |
| NM_001805 | CEBPE | CCAAT/enhancer binding protein (C/EBP), epsilon | -69.46 |
| NM_014682 | ST18 | suppression of tumorigenicity 18, zinc finger | -67.63 |
| NM_002467 | MYC | v-myc avian myelocytomatosis viral oncogene homolog | -65.46 |
| NM_005263 | GFI1 | growth factor independent 1 transcription repressor | -64.45 |
| NM_153615 | RGL4 | ral guanine nucleotide dissociation stimulator-like 4 | -63.06 |
| NM_002287 | LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 | -59.78 |
| NM_002586 | PBX2 | pre-B-cell leukemia homeobox 2 | -58.11 |
| NM_005211 | CSF1R | colony stimulating factor 1 receptor | -55.40 |
| NM_002831 | PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | -52.38 |
| NM_000442 | PECAM1 | platelet/endothelial cell adhesion molecule 1 | -52.24 |
*Folds-change of treatment group compared to control analyzed by Genespring software analysis, Moderated T-test, p<0.05)