Table 2(b).
Most up- and down-regulated genes in 5-Aza treated Kasumi 1
| Gene Bank Accession | Gene symbol |
Gene description
( Homo sapiens) |
*Folds
change |
|---|---|---|---|
| NM_021120 | DLG3 | discs, large homolog 3 (Drosophila) | 14.12 |
| NM_033114 | ZCRB1 | zinc finger CCHC-type and RNA binding motif 1 | 12.82 |
| NM_001110514 | EBF4 | early B-cell factor 4 | 12.63 |
| NM_013271 | PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | 11.11 |
| NM_003278 | CLEC3B | C-type lectin domain family 3, member B | 9.44 |
| NM_003456 | ZNF205 | zinc finger protein 205 | 9.23 |
| NM_005252 | FOS | FBJ murine osteosarcoma viral oncogene homolog | 8.83 |
| NM_002840 | PTPRF | protein tyrosine phosphatase, receptor type F | 8.83 |
| NM_019058 | DDIT4 | DNA-damage-inducible transcript 4 | 8.17 |
| NM_002728 | PRG2 | proteoglycan 2, bone marrow | 7.82 |
| NM_001122962 | SIRPB2 | signal-regulatory protein beta 2 | 7.78 |
| NM_001039580 | MAP9 | microtubule-associated protein 9 | 7.46 |
| NM_080863 | ASB16 | ankyrin repeat and SOCS box containing 16 | 7.21 |
| NM_021158 | TRIB3 | tribbles pseudokinase 3 | 6.95 |
| NM_153334 | SCARF2 | scavenger receptor class F member 2 | 6.80 |
| NM_002390 | ADAM11 | ADAM metallopeptidase domain 11 | 5.63 |
| NM_032797 | AIFM2 | apoptosis-inducing factor, mitochondrion-associated 2 | 4.98 |
| NM_004626 | WNT11 | wingless-type MMTV integration site family, member 11 | 4.90 |
| NM_032271 | TRAF7 | TNF receptor-associated factor 7, E3 ubiquitin protein ligase | 3.67 |
| NM_001015053 | HDAC5 | histone deacetylase 5 | 3.67 |
| NM_001069 | TUBB2A | tubulin, beta 2A class IIa | 2.67 |
| NM_139314 | ANGPTL4 | angiopoietin-like 4 | 2.67 |
| NM_002831 | PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | 2.27 |
| NM_001292030 | TTC39C | tetratricopeptide repeat domain 39C | -70.59 |
| NM_002844 | PTPRK | protein tyrosine phosphatase, receptor type K | -32.81 |
| NM_198481 | VSTM1 | V-set and transmembrane domain containing 1 | -32.49 |
| NM_000099 | CST3 | cystatin C | -26.47 |
| NM_001244008 | KIF1A | kinesin family member 1A | -22.49 |
| NM_001190467 | PRR36 | proline rich 36 | -21.97 |
| NM_024422 | DSC2 | desmocollin 2 | -20.96 |
| NM_001282735 | SPATS2L | spermatogenesis associated, serine-rich 2-like | -18.59 |
| NM_015238 | WWC1 | WW and C2 domain containing 1 | -16.52 |
| NM_021199 | SQRDL | sulfide quinone reductase-like (yeast) | -15.53 |
| NM_001838 | CCR7 | chemokine (C-C motif) receptor 7 | -13.97 |
| NM_000474 | TWIST1 | twist family bHLH transcription factor 1 | -13.27 |
| NM_012395 | CDK14 | cyclin-dependent kinase 14 | -13.19 |
| NM_000168 | GLI3 | GLI family zinc finger 3 | -12.65 |
| NM_024940 | DOCK5 | dedicator of cytokinesis 5 | -11.91 |
| NM_030906 | STK33 | serine/threonine kinase 33 | -11.90 |
| NM_001900 | CST5 | cystatin D | -11.86 |
| NM_006897 | HOXC9 | homeobox C9 | -11.74 |
| NM_005855 | RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | -11.55 |
| NM_033292 | CASP1 | caspase 1, apoptosis-related cysteine peptidase | -11.50 |
| AK027605 | CYP2S1 | cytochrome P450, family 2, subfamily S, polypeptide 1 | -11.02 |
| NM_003474 | ADAM12 | ADAM metallopeptidase domain 12 | -7.681 |
| NM_172217 | IL16 | interleukin 16 | -4.46 |
| NM_001025300 | RAB12 | RAB12, member RAS oncogene f | -4.89 |
*Folds-change of treatment group compared to control analyzed by Genespring software analysis, Moderated T-test, p<0.05)