Table 2(c).
Most up- and down-regulated genes in TSA+5-Aza treated Kasumi 1
| Gene Bank Accession | Gene symbol | Gene description ( Homo sapiens) | *Folds change |
|---|---|---|---|
| NM_182908 | DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 758.66 |
| NM_001080434 | LMTK3 | lemur tyrosine kinase 3 | 541.34 |
| NM_001069 | TUBB2A | tubulin, beta 2A class IIa | 435.79 |
| NM_139314 | ANGPTL4 | angiopoietin-like 4 | 429.60 |
| NM_138345 | VWA5B2 | von Willebrand factor A domain containing 5B2 | 398.46 |
| NM_030630 | HID1 | HID1 domain containing | 341.01 |
| NM_006928 | PMEL | premelanosome protein | 282.05 |
| NM_014971 | EFR3B | EFR3 homolog B (S. cerevisiae) | 263.45 |
| NM_144698 | ANKRD35 | ankyrin repeat domain 35 | 220.61 |
| NM_145056 | DACT3 | dishevelled-binding antagonist of beta-catenin | 219.77 |
| NM_004933 | CDH15 | cadherin 15, type 1, M-cadherin | 190.60 |
| NM_006086 | TUBB3 | tubulin, beta 3 class III | 173.87 |
| NM_001098722 | GNG4 | guanine nucleotide binding protein (G protein), gamma 4 | 167.50 |
| NM_080860 | RSPH1 | radial spoke head 1 homolog (Chlamydomonas) | 146.52 |
| NM_003835 | RGS9 | regulator of G-protein signaling 9 | 126.58 |
| NM_007224 | NXPH4 | neurexophilin 4 | 124.19 |
| NM_020770 | CGN | cingulin | 118.29 |
| NM_001145028 | PALM3 | paralemmin 3 | 114.39 |
| NM_000088 | COL1A1 | collagen, type I, alpha 1 | 111.63 |
| NM_003933 | BAIAP3 | BAI1-associated protein 3 | 107.26 |
| NM_017577 | GRAMD1C | GRAM domain containing 1C | 95.72 |
| NM_052899 | GPRIN1 | G protein regulated inducer of neurite outgrowth 1 | 95.72 |
| NM_005325 | HIST1H1A | histone cluster 1, H1a | 95.08 |
| NM_033141 | MAP3K9 | mitogen-activated protein kinase kinase kinase 9 | 92.48 |
| NM_198573 | ENHO | energy homeostasis associated | 92.06 |
| NM_001039570 | KREMEN1 | kringle containing transmembrane protein 1 | 91.54 |
| NM_018667 | SMPD3 | sphingomyelin phosphodiesterase 3 | 91.24 |
| NM_012253 | TKTL1 | transketolase-like 1 | 87.98 |
| NM_002599 | PDE2A | phosphodiesterase 2A, cGMP-stimulated | 84.11 |
| NM_033259 | CAMK2N2 | calcium/calmodulin-dependent protein kinase II inhibitor 2 | 80.49 |
| NM_014226 | MOK | MOK protein kinase | 79.66 |
| NM_001678 | ATP1B2 | ATPase, Na+/K+ transporting, beta 2 polypeptide | 78.33 |
| NM_006500 | MCAM | melanoma cell adhesion molecule | 75.94 |
| NM_001077621 | VPS37D | vacuolar protein sorting 37 homolog D | 74.87 |
| NM_052924 | RHPN1 | rhophilin, Rho GTPase binding protein 1 | 74.59 |
| NM_020127 | TUFT1 | tuftelin 1 | 73.36 |
| NM_001040709 | SYPL2 | synaptophysin-like 2 | 70.97 |
| NM_032432 | ABLIM2 | actin binding LIM protein family, member 2 | 70.76 |
| NM_001024401 | SBK1 | SH3 domain binding kinase 1 | 68.42 |
| NM_022742 | CCDC136 | coiled-coil domain containing 136 | 68.41 |
| NM_021979 | HSPA2 | heat shock 70kDa protein 2 | 67.51 |
| NM_000142 | FGFR3 | fibroblast growth factor receptor 3 | 65.65 |
| NM_033103 | RHPN2 | rhophilin, Rho GTPase binding protein 2 | 65.01 |
| NM_198196 | CD96 | CD96 molecule (CD96) | -228.86 |
| NM_001972 | ELANE | elastase, neutrophil expressed | -172.59 |
| NM_001244008 | KIF1A | kinesin family member 1A | -171.82 |
| NM_133374 | ZNF618 | zinc finger protein 618 | -169.32 |
| NM_020125 | SLAMF8 | SLAM family member 8 | -158.07 |
| NM_003974 | DOK2 | docking protein 2 | -153.14 |
| NM_080387 | CLEC4D | C-type lectin domain family 4, member D | -143.62 |
| NM_130782 | RGS18 | regulator of G-protein signaling 18 | -110.02 |
| NM_033101 | LGALS12 | lectin, galactoside-binding, soluble, 12 | -107.48 |
| NM_178443 | FERMT3 | fermitin family member 3 | -106.90 |
| NM_012072 | CD93 | CD93 molecule | -102.56 |
| NM_001946 | DUSP6 | dual specificity phosphatase 6 | -98.76 |
| NM_012252 | TFEC | transcription factor EC | -92.29 |
| NM_002467 | MYC | v-myc avian myelocytomatosis viral oncogene homolog | -91.05 |
| NM_001004196 | CD200 | CD200 molecule | -87.76 |
| NM_005814 | GPA33 | glycoprotein A33 (transmembrane) | -82.88 |
| NM_153615 | RGL4 | ral guanine nucleotide dissociation stimulator-like 4 | -81.77 |
| NM_080588] | PTPN7 | protein tyrosine phosphatase, non-receptor type 7 | -79.77 |
| NM_014795 | ZEB2 | zinc finger E-box binding homeobox 2 | -79.47 |
| NM_005211 | CSF1R | colony stimulating factor 1 receptor | -74.06 |
| NM_001146 | ANGPT1 | angiopoietin 1 | -70.80 |
| NM_006418 | OLFM4 | olfactomedin 4 | -70.64 |
| NM_014682 | ST18 | Homo sapiens suppression of tumorigenicity 18 | -68.89 |
| NM_177403 | RAB7B | RAB7B, member RAS oncogene family | -67.90 |
| NM_198481 | VSTM1 | V-set and transmembrane domain containing 1 | -66.89 |
| NM_005187 | CBFA2T3 | core-binding factor, runt domain, alpha subunit 2; translocated to, 3 | -61.51 |
| NM_003474 | ADAM12 | ADAM metallopeptidase domain 12 | -59.66 |
| NM_005574 | LMO2 | LIM domain only 2 | -58.27 |
| NM_080387 | CLEC4D | C-type lectin domain family 4, member D | -54.65 |
| NM_001805 | CEBPE | CCAAT/enhancer binding protein (C/EBP), epsilon | -48.73 |
*Folds-change of treatment group compared to control analyzed by Genespring software analysis, Moderated T-test, p<0.05)