Table 3(b).

Gene ontology (GO) profile after TSA, 5-Aza and TSA+5-Aza treatments in Kasumi 1

GO IDs	GO term	Genes	P-value
	Biological processes
GO:0007155	Cell adhesion	ADAM12, CDH15, COL1A1, PTPRK, PTPRF, DSC2, ATP1B2, CD96, DSC2, COL1A1, MCAM	0.00093
GO:0050900	Leukocyte migration	ANGPTL1, COL1A1, ATP1B2, PECAM1, PTPN6, DOK2	0.0013
GO:0030282	Bone mineralization	CLEC3B, WNT11, FGFR3, TUFT1	0.0014
GO:0008277	Regulation of G-protein coupled receptor protein signaling pathway	GNG4, RGS18, RGS9, RAMP1	0.0022
GO:2000147	Positive regulation of cell motility	CCR7, CSF1R, TWIST1	0.0037
GO:0006909	Phagocytosis	CEBPE, CD93, ELANE, PECAM1	0.0039
GO:0035335	Peptidyl-tyrosine dephosphorylation	PTPN6, PTPN7, PTPRK,PTPRF, DUSP6	0.0042
GO:0034394	Protein localization to cell surface	WNT11, ANGPTL1, PTPRK	0.0051
GO:0043066	Negative regulation of apoptotic process	GLI3, WNT11, ANGPTL1, ANGPTL4, CSF1R, DHRS2, TWIST1, MYC	0.0068
GO:0006468	Protein phosphorylation	FES, MOK, WNT11, CDK14, LMTK3, TRIB3, RPS6KA4	0.024
GO:0060548	Negative regulation of cell death	WNT11, CST3, MYC	0.030
GO:0030097	Hematopoiesis	ANGPTL1, CSF1R, GFI1	0.034
GO:0008285	Negative regulation of cell proliferation	PTPN6, PTPRK, GL13, CSF1R, DHRS2, DLG3CBFA2T3	0.048
GO:0042493	Response to drug	FOS, COL1A1, CST3, HDAC5, MYC	0.062
GO:0001525	Angiogenesis	ANGPTL1, ANGPTL4, PECAM1, RAMP1, MCAM	0.096
GO:0007017	Microtubule-based process	TUBB2A, TUBB3	0.10
	Molecular Functions
GO:0004725	Protein tyrosine phosphatase activity	PTPN6, PTPN7, PTPRF, PTPRK, DUSP6	0.0038
GO:0005001	Transmembrane receptor protein tyrosine phosphatase activity	PTPN6, PTPRF, PTPRK	0.0051
GO:0030246	Carbohydrate binding	CLEC3B, CLEC4B, PRG2, LGALS12	0.036
GO:0004672	Protein kinase activity	MOK, TRIB3, CDK14, LMTK3, STK33, MAP3K9	0.078
GO:0008201	Heparin binding	CLEC3B, ELANE, PTPRF, PRG2	0.081
GO:0004674	protein serine/threonine kinase activity	MOK, SBK1, LMTK3, MAP3K9, RPS6KA4, STK33	0.091
GO:0008013	Beta-catenin binding	GLI3, DACT3, PTPRK	0.095
GO:0003700	Transcription factor binding	FOS, PBX2, HDAC5, TWIST1, MYC	0.100
	Pathways
	Transcriptional misregulation in cancer	CEBPE, LMO2, CSF1R, CDK14, MYC, ELANE	0.0014
	MAPK signaling pathway	FOS, PTPN7, MYC, RPS6KA4	0.010
	PI3K-Akt signaling pathway	DDIT4, GNG4, ANGPTL1, COL1A1, CSF1R, FGFR3, MYC	0.041
	Pathway in cancer	FOS, GNG4, GLI3, WNT11, CSF1R, FGFR3, MYC	0.069
	Hippo signaling pathway	WWCI, WNT11, MYC, DLG3	0.10
	Proteoglycans in cancer	WNT11, PTPN6, TWIST1, MYC	0.18
	Ras signaling	GNG4, ANGPTL4, CSF1R, FGFR3	0.23
	Phagosome	TUBB2A, TUBB3	0.10

(DAVID software analysis, EASE score, p< 0.1)