Table 3.
Univariate | Multivariate | ||||||
---|---|---|---|---|---|---|---|
Risk factors present on admission | Difference in median LOS (hours) * | 95%CI | P‐value | Difference in median LOS (hours) * | 95%CI | P‐value | |
Continuous | Spearman correlation | ||||||
Age (months) | −0.2 | −1.2 | (−2.1, −0.2) | 0.02 | −0.6 | (−1.6, 0.5) | 0.3 |
Gestational age (weeks) | 0.09 | 0.7 | (−0.7, 2.0) | 0.3 | |||
Birth weight (kg) | 0.03 | −0.0 | (−5.7, 6.2) | 0.9 | |||
Severity score on admission (points) | 0.2 | 3.1 | (1.1, 5.1) | 0.002 | 3.0 | (0.7, 5.1) | 0.01 |
Categorical | Geometric mean LOS (hours) | ||||||
Gender | |||||||
Female | 61 | −1.4 | (−9.4, 8.0) | 0.8 | |||
Male | 62 | (reference) | |||||
Currently breastfed | |||||||
Yes | 62 | 1.9 | (−8.9, 15.1) | 0.7 | |||
No | 60 | (reference) | |||||
Previous respiratory hospitalisation | |||||||
Yes | 60 | −2.0 | (−11.1, 9.0) | 0.7 | |||
No | 62 | (reference) | |||||
Mother smoked during pregnancy | |||||||
Yes | 62 | 1.7 | (−6.6, 11.4) | 0.7 | |||
No | 60 | (reference) | |||||
Exposed to household smoke | |||||||
Yes | 62 | 0.2 | (−8.0, 9.8) | 0.9 | |||
No | 61 | (reference) | |||||
Antibiotics before hospitalisation | |||||||
Yes | 61 | −7.1 | (−14.4, 1.4) | 0.09 | −2.4 | (−11, 7.6) | 0.6 |
No | 69 | (reference) | |||||
Any virus detected | |||||||
Yes | 64 | 8.7 | (−1.9, 21.3) | 0.11 | |||
No | 55 | (reference) | |||||
RSV | |||||||
Yes | 66 | 7.0 | (−2.2, 17.2) | 0.14 | 10.0 | (−0.6, 22.3) | 0.06 |
No | 58 | (reference) | |||||
HRV | |||||||
Yes | 64 | 3.4 | (−6.1, 14.6) | 0.5 | |||
No | 61 | (reference) | |||||
RSV and HRV | |||||||
Yes | 64 | 5.0 | (−3.8, 15.1) | 0.3 | |||
No | 59 | (reference) | |||||
Adenovirus | |||||||
Yes | 57 | −4.4 | (−18.3, 14.3) | 0.6 | |||
No | 62 | (reference) | |||||
Any bacteria detected | |||||||
Yes | 63 | 3.1 | (−5.7, 13.4) | 0.5 | |||
No | 59 | (reference) | |||||
Virus/bacteria interaction | 0.3 | ||||||
Virus negative/Bacteria negative | 58 | (reference) | |||||
Virus negative/Bacteria positive | 53 | −5.0 | (−19.1, 14.2) | 0.6 | |||
Virus positive/Bacteria negative | 60 | 1.5 | (−13.2, 21.0) | 0.9 | |||
Virus positive/Bacteria positive | 65 | 7.0 | (−7.9, 26.0) | 0.4 |
On univariate analysis, factors at enrolment associated with prolonged LOS were age and severity score. On multivariate analysis, only severity score remained significant.
Arising as a re‐expression of the multiplicative effect on the geometric mean from a linear regression on log (LOS).