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. 2004 May 7;203(2):631–637. doi: 10.1002/path.1570

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Copyright © 2004 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.

This article is being made freely available through PubMed Central as part of the COVID-19 public health emergency response. It can be used for unrestricted research re-use and analysis in any form or by any means with acknowledgement of the original source, for the duration of the public health emergency.

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Normal lung tissue: overview (A) and larger magnification (B). Positive staining for ACE2 is clearly present on alveolar epithelial cells (arrow) and capillary endothelium (arrow‐head). Fibrotic lung tissue (C) and larger magnification (D). Positive staining for ACE2 is clearly present on type II cells (arrow). Cultured lung type II alveolar epithelial cells (A549) are strongly positive for ACE2 (E). Control section stained with anti‐ACE2 in the presence of the synthetic ACE2 peptide shows no staining of lung tissue (F)