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. 2020 Feb 7;9(2):69. doi: 10.3390/antibiotics9020069

Table 8.

MICs of berberines I15–I22.

Strain MIC (μM)
I15 I16 I17 I18 I19 I20 I21 I22
S. aureus ATCC 29213 360 3.50 7.35 4.15 3.09 2.80 2.72 2.02
S. aureus ATCC 25923 3.09 4.04
S. aureus ATCC 29247 * 360 7.00 2.80
S. aureus ATCC BAA-41 ** 551 7.00 4.15 3.09 2.80 5.45 4.04
S. aureus ATCC 33591 ** 3.67 3.09 5.45
S. aureus ATCC 33592 ** 3.09
S. aureus ATCC 43300 ** 3.67 3.09 2.72 8.07
S. aureus ATCC BAA-1717 ** 3.09 2.80
S. aureus ATCC BAA-1720 ** 3.09 2.80
S. aureus ATCC BAA-1747 ** 2.80
S. aureus ATCC BAA-976 ** 3.67
S. aureus ATCC BAA-1708 ** 7.35
S. epidermidis ATCC 12228 360 3.50 1.54 1.40 1.36
E. faecium ATCC 49624 >551 7.00 8.31 3.09 3.74 1.36 4.04
E. faecium ATCC 700221 *** >551 7.00 8.31 3.09 3.74 2.72 8.07
E. faecalis ATCC 29212 >551 7.00 6.17 2.80 1.36 8.07
E. faecalis ATCC 51575 6.17 2.80
B. subtilis 168 360 7.00 4.15 0.77 2.80 2.72 8.07
E. coli ATCC 25922 >1405 56.0 12.4 6.17 5.61 5.45 >129
E. coli ATCC BAA−2469 § 12.4 6.17 5.61 5.45 >129
P. aeruginosa ATCC BAA-2108 §§ 100 24.7 11.2 10.9 >129
K. pneumoniae ATCC BAA-2470 § 100 >129
K. pneumoniae ATCC BAA-1144 § >1405 112 24.7 44.9 87.2
A. baumannii ATCC 19606 §§ 24.7 87.2 >129
Enterobacter cloacae BAA-1143 § >129

* Ampicillin−resistant, ** methicillin resistant, *** vancomycin−resistant, § expresses beta−lactamases, §§ MDR.