Figure 5.

Schematic representation of the TEG^® 5000 system. Thromboelastography conducted with the TEG^® 5000 system uses approximately 0.36 mL of blood, which is placed into a cylindrical cup at 37 °C. A pin on a torsion wire is suspended in the blood, and the cup rotates in alternating directions (rotation angle 4°45’, cycle duration 10 s) to simulate venous flow. At the onset of each measurement, there is no torque between the cup and the pin, and the machine provides a reading of zero. As clotting occurs, fibrin fibers formed between the pin and the cup create a rotational force on the pin, which is measured via a torsion wire and an electromagnetic transducer; the readout line diverges from the baseline until it reaches a maximum value (maximum clot strength). With the onset of clot lysis, the readout converges back towards baseline. Reproduced with permission from Haemonetics [11].