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. 2020 Jan 19;9(1):36. doi: 10.3390/antibiotics9010036

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Colloidal silver presents bactericidal activity against Gram-negative and Gram-positive bacteria. Time–kill curves of susceptible and multidrug-resistant (MDR) strains of Acinetobacter baumannii (ATCC 17978 and #11) (A), Pseudomonas aeruginosa (PAO1 and Pa238) (B), Escherichia coli (ATCC 25922 and Ecmcr1+) (C), Staphylococcus aureus (Sa24 and USA300#1) (D), and Enterococcus faecalis (VS and VR) (E) in the presence of 0.5×, 1×, and 2× minimal inhibitory concentration (MIC) of colloidal silver for 24 h. CTL: control, bacteria without treatment. The MICs of colloidal silver against ATCC 17978, #11, PAO1, Pa238, ATCC 25922, Ecmcr1+, E. faecalis VS, E. faecalis VR, Sa24, and USA300#1 were 4, 4, 4, 8, 4, 8, 8, 8, 8, and 8 mg/L, respectively.