Table 2.
Capabilities and main features of the selected drug–drug interaction software platforms.
| DDI Software Platform | Lexicomp Drug Interactions | Drugs.com | Epocrates Online | Medscape | iDoctus | Medimecum | Guía IF |
|---|---|---|---|---|---|---|---|
| Language | English | English | English | English | Spanish | Spanish | Spanish |
| Online / Offline * | Online | Online | Online | Online | Offline | Offline | Offline |
| Clinical effect | Yes | Yes | Yes | Yes | Yes | Sometimes | Sometimes |
| Severity | Yes | Yes | No | Sometimes | Yes | No | Sometimes |
| Mechanism of interaction | Yes | Yes | Yes | Yes | Yes | No | Sometimes |
| Recommendations for clinical management | Yes | Yes | Yes | Yes | Yes | Yes | Sometimes |
| Display of the level of evidence | Yes | No | No | No | Yes | No | No |
| Reference list | Yes | Yes | No | No | Yes | No | Sometimes |
| Date of last update ** | 2019 | 02/12/2019 | Not available | 11/12/2017 | Not available | Not available | 15/04/2014 |
| Source | Wolters Kluwer Clinical Drug Information | Micromedex® Cerner Multum Wolters Kluwer American Society of Health System Pharmacists |
Athenahealth ® | Medscape Publishers’ Circle® | Consejo General de Colegios Oficiales Farmacéuticos | Springer Healthcare Ibérica® | Sociedad Española de Farmacia Hospitalaria |
* Online means platform is only available with Internet connection (desktop computer or smartphone app). Offline means the platform can be used without Internet connection (desktop computer or smartphone app). ** The last update indicated in each platform, checked on the 21st of December 2019.