Table 3.
Ability of drug–drug interactions (DDIs) software platforms to detect antimicrobial-drug interactions (ADIs).
| DDI Software Platform | Lexicomp Drug Interactions | Drugs.com | Epocrates online | Medscape | iDoctus | Medimecum | Guía IF |
|---|---|---|---|---|---|---|---|
| Trimethoprim/Enalapril | Yes | Yes | Yes | Yes | Yes | No | No |
| Linezolid/Metoclopramide | Yes | Yes | Yes | No | No | No | No |
| Levofloxacin/Systemic prednisone | Yes | Yes | Yes | Yes | No | Yes | No |
| Escitalopram/Ciprofloxacin | Yes | Yes | No | No | Yes | Yes | No |
| Levofloxacin/antacids | Yes | Yes | Yes | No | Yes | Yes | Yes |
| Meropenem/valproic acid | Yes | Yes | Yes | Yes | Yes | Yes | No |
| Quinolones/NSAIDs | Yes | Yes | Yes | Yes | No | Yes | Yes |
| Cefditoren/omeprazole | Yes | Yes | Yes | No | No | No | No |
| Rifampicin/Apixaban | Yes | Yes | Yes | Yes | Yes | Yes | Yes |
| Fluconazole/Diltiazem | Yes | Yes | No | Yes | Yes | Yes | Yes |
| Sensitivity | 100% | 100% | 80% | 60% | 60% | 70% | 40% |