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. 2020 Jan 13;8(1):13. doi: 10.3390/biomedicines8010013

Figure 2.

Figure 2

(a) Schematic representation of PLA-based NPs having different coating materials. (b) Population and morphology of NPs using TEM (scale bar = 100 nm). (c) Characterization of NPs for hydrodynamic diameters using dynamic light scattering (d), zeta potential using laser doppler anemometry (e), and analysis of particle size (in CSF at 37 °C) is observed as stable and no measurable aggregation was observed up to 24 h. Reproduced with permission from Song, E.; Gaudin, A.; King, A.R.; Seo, Y.E.; Suh, H.W.; Deng, Y.; Cui, J.; Tietjen, G.T.; Huttner, A.; Saltzman, W.M. Surface chemistry governs cellular tropism of nanoparticles in the brain. Nat. Commun. 2017 [108].