Table 1.
The characteristics of patients
| Factor | Sole rhinovirus n = 58 | Sole RSV n = 35 | Sole enteroviruses n = 34 | Sole bocavirus n = 12 | Sole other virus n = 8 | ≥2 viruses n = 87 | No virus n = 13 |
|---|---|---|---|---|---|---|---|
| Age, (years) | 2.2 (1.2, 3.6) | 0.9 (0.5, 1.5) | 2.8 (1.7, 5.8) | 1.4 (1.1, 2.2) | 0.6 (0.5, 2.8) | 1.5 (1.1, 2.5) | 1.1 (0.8, 1.9) |
| Male, No. | 38 (66%) | 19 (54%) | 25 (74%) | 9 (75%) | 6 (75%) | 62 (72%) | 6 (46%) |
| Any sensitization, No.* | 36 (62%) | 4/34 (12%) | 18/33 (55%) | 5 (42%) | 1 (13%) | 27 (31%) | 2 (15%) |
| Number of sensitizations, No. | 1 (0, 3) | 0 (0, 0) | 1 (0, 3) | 0 (0, 1) | 0 (0, 0) | 0 (0, 1) | 0 (0, 0) |
| Total IgE level, kU/l† | 58 (22, 298) | 8 (3, 28) | 86 (36, 160) | 24 (15, 98) | 14 (10, 79) | 18 (5, 113) | 31 (3, 47) |
| Blood eosinophils, × 109/l | 0.4 (0.2, 0.5) | 0.0 (0.0, 0.1) | 0.5 (0.3, 0.7) | 0.3 (0.2, 0.5) | 0.0 (0.0, 0.3) | 0.2 (0.1, 0.5) | 0.1 (0.1, 0.3) |
| Nasal eosinophils, 4‐point scale 0–3‡ | 1 (0, 2) | 0 (0, 0) | 2 (0, 2) | 1 (0, 1) | 0 (0, 1) | 0 (0, 1) | 0 (0, 0) |
| Exhaled nitric oxide, ppb | 6.5 (5.1, 8.3) | 3.9 (3.2, 5.2) | 6.8 (5.4, 11) | 4.8 (4.1, 12) | 6.1 (5.4, 9.8) | 5.8 (4.0, 8.4) | 4.2 (2.0, 6.0) |
| Atopic eczema, No. | 18/56 (32%) | 3/34 (9%) | 12/33 (36%) | 1 (8%) | 0 (0%) | 17 (20%) | 0 (0%) |
Values are medians (interquartile range), unless otherwise noted.
IgE, immunoglobulin E; ppb, parts per billion; RSV, respiratory syncytial virus.
*Any sensitization was defined as positive immunoglobulin (Ig) E antibodies to any of the common allergens (cut‐off level 0.35 kU/l for codfish, cow’s milk, egg, peanut, soybean, wheat, cat, dog, horse, birch, mugwort, timothy, Cladosporium herbarum and Dermatophagoides pteronyssinus; fluoro‐enzyme immunoassay, CAP FEIA, Phadiatop Combi®, Phadia, Uppsala, Sweden).
†Data available: rhinovirus (n = 57), RSV (n = 34), enteroviruses (n = 32), bocavirus (n = 12), other virus (n = 8), ≥2 viruses (n = 83) and no virus (n = 13).
‡Data available: rhinovirus (n = 53), RSV (n = 33), enteroviruses (n = 32), bocavirus (n = 11), other virus (n = 7), ≥2 viruses (n = 77) and no virus (n = 11).