Table 2.
The relationship of gene expression with the development of metastases—ROC analysis.
| Gene | Area under ROC Curve (AUC) | 95% CI | Cutoff Value | Significance Level p (Area = 0.5) |
Sensitivity | Specificity |
|---|---|---|---|---|---|---|
| CA9 | 0.891 | 0.804–0.978 | ≤2.6 | <0.001 | 79.41 | 90.91 |
| NDUFA4L2 | 0.811 | 0.672–0.951 | ≤27 | <0.001 | 94.12 | 68.18 |
| VWF | 0.788 | 0.659–0.917 | ≤1.4 | <0.001 | 70.59 | 81.82 |
| BHLHE41 | 0.808 | 0.691–0.925 | ≤2.6 | <0.001 | 88.24 | 63.64 |
| EGLN3 | 0.873 | 0.760–0.986 | ≤3.5 | <0.001 | 97.06 | 68.18 |
| IGFBP3 | 0.714 | 0.572–0.856 | ≤1.7 | 0.003 | 73.53 | 68.18 |
| SAA1 | 0.689 | 0.537–0.841 | >0.5 | 0.015 | 64.71 | 77.27 |
| CSF1R | 0.547 | 0.389–0.705 | ≤2.1 | 0.562 | - | - |
| C1QA | 0.693 | 0.552–0.833 | ≤3.7 | 0.007 | 91.18 | 40.91 |
| FN1 | 0.568 | 0.412–0.724 | ≤0.8 | 0.198 | - | - |