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. 2020 Jan 4;8(1):5. doi: 10.3390/biomedicines8010005

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Exposure to THC during gastrulation alters escape response parameters. Analysis and quantification of C-bend parameters was carried out at 2 dpf. Zebrafish embryos exhibit a C-bend in response to a jet of water directed at the head just behind the eyes. (A) Bar graph shows the maximum angle of bend for vehicle and THC-treated (6 mg/L) embryos. (B) Shows the instantaneous peak speed (mm/s) during c-bend. (C) Shows the instantaneous peak acceleration during C-bend. (D) Bar graph showing the time for the tail to bend to the maximum angle. * Significantly different from vehicle control, p < 0.05.