Table 2.
Follow-up characteristics of connective tissue disease patients in the two cohorts combined.
| 1st Follow-up | 2nd Follow-up | ||
|---|---|---|---|
| N (%) | 69 (100%) | 27 (39%) | |
| Age (years) | 61.35 ± 12.25 | 61.80 ± 11.85 | |
| Female gender (%) | 59 (86) | 24 (89) | |
| Underlying disease | SSc | 58 (84) | 24 (89) |
| MCTD | 6 (9) | 1 (4) | |
| SLE | 5 (7) | 2 (7) | |
| Time to follow-up (months) | 9.47 ± 7.29 | 8.29 ± 4.36 | |
| NYHA stage (%) | I | 2 (3) | - |
| II | 32 (46) | 14 (52) | |
| III | 33 (48) | 13 (48) | |
| IV | 2 (3) | - | |
| Echo-derived PASP (mmHg) | 62.65 ± 20.30 | 68.70 ± 26.90 | |
| RHC-derived PASP (mmHg) | 56.65 ± 16.5 | 65.30 ± 18.63 | |
| PVR (wood units) | 6.02 ± 3.04 | 7.34 ± 3.15 | |
| Cardiac Index | 2.68 ± 0.59 | 2.51 ± 0.37 | |
| RAP (mmHg) | 7.33 ± 4.3 | 7.26 ± 4.06 | |
| NT-pro-BNP (pg/mL) | 1197.89 ± 1507.77 (n = 54) | 1356.4 ± 1300.64 (n = 20) | |
| 6mWD (m) | 389.20 ± 83.94 (n = 46) | 412.0 ± 79.28 (n = 16) | |
Continuous values are presented as mean ± SD. (SSc: Systemic Sclerosis, MCTD: Mixed Connective Tissue Disease, SLE: Systemic Lupus Erythematosus, NYHA: New York Heart Association, PASP: Pulmonary Artery Systolic Pressure, RHC: Right Heart Catheterization, PVR: Pulmonary Artery Resistance, RAP: Right Atrial Pressure, NT-pro-BNP: N-terminal pro Brain Natriuretic Peptide, 6mWD: 6 min Walking Distance).