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. 2020 Feb 2;9(2):24. doi: 10.3390/biology9020024

Figure 3.

Figure 3

Effects of AG on the pathological symptoms in the HFD-propelled CAC mice model. The animals were randomly divided into six groups: normal group, HFD+AOM/DSS group (AOM/DSS-induced CAC mice fed HFD), 5-ASA group (CAC-induced mice fed on a HFD which was administered with 5-ASA 75 mg/kg daily, p.o.), CPT group (CAC-induced mice fed on a HFD which was administered with CPT 0.5 mg/kg daily, i.p.), and AG 25 and 50 group (CAC-induced mice fed on a HFD which was administered with AG 25 and 50 mg/kg daily, p.o.). (A) The survival ratio, (B) body weight, and (C) splenic weight were measured in each mouse. The values are the mean ± SD (n = 10); ## p < 0.01, ### p < 0.001 vs. normal group; * p < 0.05, ** p < 0.01, *** p < 0.001 vs. the HFD+AOM/DSS group; significant differences between the treated groups were determined by ANOVA and Dunnett’s post-hoc test.