Figure 7.

Effects of AG on STAT3 and STAT3 target protein expression in the HFD-propelled CAC mice model. (A) The protein extracts were prepared from the colon tissues and western blot analysis was performed for the detection of pSTAT3 (Tyr705), Cdk4, and Bcl-2 protein expression using specific antibodies. The relative protein level was determined by densitometric analysis normalized to the internal controls. The values are the mean ± SD (n = 10); ^### p < 0.001 vs. normal group; *** p < 0.001 vs. the HFD+AOM/DSS group; significant differences between the treated groups were determined by ANOVA and Dunnett’s post-hoc test.