Table 1.

Well-characterised bacteriocins isolated from Staphylococcus species.

Class	Subclass	Subtype	Bacteriocin	Producing Strain	Inhibits S. aureus: Strain (MIC)	in vivo Model	References
I	Ia	A1	BacCh91 *	S. aureus CH9/DSM26258	in vitro: ATCC25923, Newman, M-122, RN4220 (4.0–6.0 μM)		[92]
			Epicidin 280 *	S. epidermidis BN280			[70]
			Epidermin *	S. epidermidis Tü3298	in vitro		[74,93]
			Epilancin 15X *	S. epidermidis 15X154			[94]
			Epilancin K7 *	S. epidermidis K7			[69]
			Gallidermin *	S. gallinarum F16/P57 Tü3298	in vitro: ATCC29213, CCUG35601 (1.25–8.0 μg/mL)		[75,95,96]
			Hominicin	S. hominis MBBL2–9	in vitro: ATCC25923, ATCC11435, CCAR M3501 (0.06–3.82 μg/mL)		[97,98]
			Hyicin 3682	S. hyicus 3682	in vitro		[99,100]
			Nisin J	S. capitis APC2923	in vitro		[20]
			Pep5	S. epidermidis 5	in vitro		[73,74,93]
		A2	Nukacin ISK-1 **	S. warneri Nukadoko/S. simulans 3299			[101]
			Warnericin RB4	S. warneri RB4			[102]
	Ic		Hyicin 4244	S. hyicus 4244	in vitro		[83,103]
II	IIb	S	Aureocin A70	S. aureus A70			[104]
		S	C55 *	S. aureus C55			[67]
	IId		Aureocin A53 *	S. aureus A53			[66,74]
			BacSp222 **	S. pseudintermedius	in vitro: DSM26258, MRSA USA300, KB/8568, ATCC25923 (0.89–1.30 μM)		[52]
II	IId		Capidermicin	S. capitis CIT060	in vitro: NCDO1499, DPC5297, Newman, RF122 (3.1–10 μg/mL)		[105]
			Epidermicin NI01 *	S. epidermidis 224	in vitro: 1195, MRSA s37, MRSA s41, MRSA s71 (1.0–2.0 μg/mL)	greater wax moth, cotton rat	[64,106,107]
III	IIIa		Endopeptidase ALE-1 †	S. capitis EPk1			[108]
			Lysostaphin **	S. simulans biovar Staphylolyticus ATCC1362	in vitro (0.002–100 μg/mL)	rat, mouse, cotton rat, rabbit, human	[87,88,90,109,110,111,112,113,114,115,116,117,118,119]
IV			Aureocyclicin 4185	S. aureus 4185			[91]

Chemical structure available from: * https://www.bactibase.hammamilab.org; ** https://www.ncbi.nlm.nih.gov/Structure; † https://www.rcsb.org; all other chemical structures available from references stylised in bold.