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Analysis of the FDA-approved new drugs between January 1999 and December 2019. (A) Annual number of the total FDA-approved new drugs (black) and peptide/protein therapeutics (gray). (B) Known mechanisms of the FDA-approved peptide/protein therapeutics. “Inhibitor” includes membrane inhibition as well as other mechanisms of action. The raw data were collected from Drugs@FDA (http://www.fda.gov/drugsatfda).
