Skip to main content
. 2011 May 9;30(6):1203–1224. doi: 10.1002/mas.20320

Figure 3.

Figure 3

Schematic diagram of a proteomic approach to identify microorganisms based on MS/MS analysis. Microbial proteins are extracted and chemically or biochemically digested. The peptide digests are separated with chromatography and analyzed with MS/MS. The MS/MS spectra are checked against a proteome database to identify the proteins and to deduce the source microorganism. Mathematical algorithms might be applied to evaluate the search results before the microorganisms are identified. [Color figure can be viewed in the online issue, which is available at wileyonlinelibrary.com]