Table 3.
Sample | IC50 (µg/mL) | CC50 (µg/mL) | SI |
---|---|---|---|
Triterpenoids | |||
Glycyrrhizin | 180 | 560 | 3.1 |
Glycyrrhizic acid monoammonium | 320 | 690 | 2.2 |
Glycyrrhetic acid 3‐O‐glucuronide | >30b | >30 | na |
Glycyrrhetinic acid | 40.0 | 77.4 | 1.9 |
Licorice‐saponin G2 | >30b | >30 | na |
Licorice‐saponin H2 | >30b | >30 | na |
Coumarins | |||
Glycycoumarin (isolated) | 8.8 | 69.0 | 7.8 |
Glycyrin (isolated) | 7.2 | 25.0 | 3.5 |
Glycyrol (isolated) | 4.6 | 35.5 | 7.7 |
Flavonoids | |||
Flavanones | |||
Liquiritin | 75.0 | 570 | 7.6 |
Liquiritigenin | 16.4 | 125 | 7.6 |
Chalcones | |||
Isoliquiritigenin | 3.7 | 11.0 | 3.0 |
Licochalcone Aa | 2.5 | 20.0 | 8.0 |
Isoflavan | |||
Glabridina | 6.2 | 22.7 | 3.7 |
Not detected in G. uralensis 34.
No detectable HCV inhibition at 30 μg/mL. na, not applicable.