Table 2.
ESI‐MS data and the HLA‐A*0201 binding affinity and stability of the candidate peptides
| Protein | Peptide | ESI‐MS [M + H]+ | FI | DC50 | |
|---|---|---|---|---|---|
| Calculated Observed | |||||
| Rv3425 | p118 | 843.1 | 843.2 | 0.79 | > 2 hr |
| p43 | 1062.1 | 1062.2 | 0.64 | < 2 hr | |
| p29 | 1078.2 | 1078.3 | 0.32 | < 2 hr | |
| COX‐2 | p321a | 999.6 | 1000.3 | 1.16 | > 4 hr |
DC50, half‐life of disassociation of peptide/HLA‐A*0201 complexes; FI, (MFI of the peptide ‐ MFI background)/(MFI background).
aPositive peptide.