Figure 5.

Amino acid variants of the 13 complete HE genes in this study. The figures in the box indicate the identical amino acid change sites in all 13 strains in this study compared with the BCoV prototype strain Mebus HE sequence; the figure marked with triangle was an unique aa variant in the 9/10 recombinant HE sequences, and the figure marked with circular was an unique aa variant in the 10 recombinant HE sequences in this study and two other Chinese strains (GenBank accession number KU886219, MH810163), which compared with the other available BCoV HE sequences in the GenBank database. Recombination domain is located at E‐loop, R1‐loop, R2‐loop and R3‐loop between esterase and lectin domain of HE. E, esterase domain; MP, membrane‐proximal domain; R, lectin domain; SP, signal peptide