Table 3.
Groups | Liver TNF-α | Pancreas TNF-α | Liver MDA | Pancreas MDA |
---|---|---|---|---|
Control | 53.6 ± 5.9 | 25.6 ± 5.8 | 2.2 ± 0.21 | 0.52 ± 0.15 |
CP-intoxicated | 132.3 ± 6.8 a | 151.3 ± 6.9 a | 13.3 ± 0.57 a | 1.36 ± 0.06 a |
CP + EPO (5 mg/kg) | 83.3 ± 6.7 ab | 78.3 ± 6.6 ab | 6 ± 0.78 ab | 0.59 ± 0.08 b |
CP + EPO (10 mg/kg) | 56 ± 3.8 bc | 41.3 ± 3.9 ab | 3.9 ± 0.39 abc | 0.39 ± 0.04 b |
CP: cyclophosphamide, EPO: evening primrose oil, MDA: Malondialdehyde, TNF: Tumor necrosis factor. All data were expressed as mean ± SEM and analyzed using the one-way ANOVA followed by Bonferroni’s post-hoc test at p ˂ 0.05. a Significantly different from control mice, b Significantly different from CP-intoxicated mice, c Significantly different from CP + EPO (5 mg/kg) mice.