Figure 4.
Effect of the hydroethanolic extract and fractions of P. insignis on the adhesion property of C. albicans (A) and C. glabrata (B). Cells were treated for 1.5 h and adhesion was analyzed for the reference strains in terms of CFU/mL. PBS, inoculum diluent (1 × 107 cells/mL), and 1% DMSO were used as controls. Data were analyzed in relation to the PBS control by an analysis of variance with Tukey’s post-test, considering p < 0.05, and are represented as the mean ± standard deviation. (**) p < 0.01; (****) p < 0.0001; (#) p < 0.0001 with respect to PiHE, DCMF, and AMB; (@) p < 0.0001 with respect to PIHE and DCMF. AMB, amphotericin B; FLZ, fluconazole; PiHE, hydroethanolic extract of P. insignis; DCMF, dichloromethane fraction; EAF, ethyl acetate fraction. The tests were performed in quadruplicate.